Protein-Peptide Turnover Profiling reveals the order of PTM addition and removal during protein maturation

Post-translational modifications (PTMs) regulate various aspects of protein function, including degradation. Mass spectrometric methods relying on pulsed metabolic labeling are popular to quantify turnover rates on a proteome-wide scale. Such data have traditionally been interpreted in the context o...

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Detalles Bibliográficos
Autores principales: Hammarén, Henrik M., Geissen, Eva-Maria, Potel, Clement M., Beck, Martin, Savitski, Mikhail M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718778/
https://www.ncbi.nlm.nih.gov/pubmed/36460637
http://dx.doi.org/10.1038/s41467-022-35054-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718778/
https://www.ncbi.nlm.nih.gov/pubmed/36460637
http://dx.doi.org/10.1038/s41467-022-35054-2

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