Cargando…

Metabolomic profiling for dyslipidemia in pediatric patients with sickle cell disease, on behalf of the IHCC consortium

BACKGROUND: Previous study has shown that dyslipidemia is common in patients with Sickle cell disease (SCD) and is associated with more serious SCD complications. METHODS: This study investigated systematically dyslipidemia in SCD using a state-of-art nuclear magnetic resonance (NMR) metabolomics pl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qu, Hui-Qi, Glessner, Joseph, Qu, Jingchun, Mentch, Frank, Campbell, Ian, Sleiman, Patrick, Connolly, John J, Hakonarson, Hakon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718871/ https://www.ncbi.nlm.nih.gov/pubmed/36459297 http://dx.doi.org/10.1007/s11306-022-01954-z

Ejemplares similares

Metabolomic profiling of samples from pediatric patients with asthma unveils deficient nutrients in African Americans
por: Qu, Hui-Qi, et al.
Publicado: (2022)

Assessing the functional consequence of loss of function variants using electronic medical record and large-scale genomics consortium efforts
por: Sleiman, Patrick, et al.
Publicado: (2014)

COVID-19 in pediatrics: Genetic susceptibility
por: Glessner, Joseph T., et al.
Publicado: (2022)

Burden of rare coding variants reveals genetic heterogeneity between obese and non-obese asthma patients in the African American population
por: Liu, Yichuan, et al.
Publicado: (2022)

Application of deep learning algorithm on whole genome sequencing data uncovers structural variants associated with multiple mental disorders in African American patients
por: Liu, Yichuan, et al.
Publicado: (2022)

Mitochondrial DNA haplogroups and risk of attention deficit and hyperactivity disorder in European Americans
por: Chang, Xiao, et al.
Publicado: (2020)

Mendelian randomization study of obesity and type 2 diabetes in hospitalized COVID-19 patients
por: Qu, Hui-Qi, et al.
Publicado: (2022)

Copy number variation analysis in the context of electronic medical records and large-scale genomics consortium efforts
por: Connolly, John J., et al.
Publicado: (2014)

Machine Learning Reduced Gene/Non-Coding RNA Features That Classify Schizophrenia Patients Accurately and Highlight Insightful Gene Clusters
por: Liu, Yichuan, et al.
Publicado: (2021)

Circulating LIGHT (TNFSF14) and Interleukin-18 Levels in Sepsis-Induced Multi-Organ Injuries
por: Qu, Hui-Qi, et al.
Publicado: (2022)

An electronic health record (EHR) phenotype algorithm to identify patients with attention deficit hyperactivity disorders (ADHD) and psychiatric comorbidities
por: Slaby, Isabella, et al.
Publicado: (2022)

Rare Recurrent Variants in Noncoding Regions Impact Attention-Deficit Hyperactivity Disorder (ADHD) Gene Networks in Children of both African American and European American Ancestry
por: Liu, Yichuan, et al.
Publicado: (2021)

Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients
por: Qu, Jingchun, et al.
Publicado: (2021)

Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
por: Qu, Hui-Qi, et al.
Publicado: (2021)

Trans‐ethnic polygenic risk scores for body mass index: An international hundred K+ cohorts consortium study
por: Qu, Hui‐Qi, et al.
Publicado: (2023)

Expansion of Schizophrenia Gene Network Knowledge Using Machine Learning Selected Signals From Dorsolateral Prefrontal Cortex and Amygdala RNA-seq Data
por: Liu, Yichuan, et al.
Publicado: (2022)

Genomic variants exclusively identified in children with birth defects and concurrent malignant tumors predispose to cancer development
por: Liu, Yichuan, et al.
Publicado: (2023)

Genetic correlations between COVID-19 and a variety of traits and diseases
por: Chang, Xiao, et al.
Publicado: (2021)

HIF-1α Pulmonary Phenotype Wide Association Study Unveils a Link to Inflammatory Airway Conditions
por: Kelchtermans, Jelte, et al.
Publicado: (2021)

Identification of risk variants related to malignant tumors in children with birth defects by whole genome sequencing
por: Liu, Yichuan, et al.
Publicado: (2022)

Genomic information of children with malignant brain tumors for the prediction of length of hospitalization
por: Liu, Yichuan, et al.
Publicado: (2023)

Non-coding structural variation differentially impacts attention-deficit hyperactivity disorder (ADHD) gene networks in African American vs Caucasian children
por: Liu, Yichuan, et al.
Publicado: (2020)

Association of Rare Recurrent Copy Number Variants With Congenital Heart Defects Based on Next-Generation Sequencing Data From Family Trios
por: Liu, Yichuan, et al.
Publicado: (2019)

Rare recurrent copy number variations in metabotropic glutamate receptor interacting genes in children with neurodevelopmental disorders
por: Glessner, Joseph T., et al.
Publicado: (2023)

Common variants in polygenic schizophrenia
por: Glessner, Joseph T, et al.
Publicado: (2009)

Expression Pattern of the SARS-CoV-2 Entry Genes ACE2 and TMPRSS2 in the Respiratory Tract
por: Liu, Yichuan, et al.
Publicado: (2020)

A novel heterotaxy gene: Expansion of the phenotype of TTC21B‐spectrum disease
por: Strong, Alanna, et al.
Publicado: (2021)

Genetic Variation in Genes Encoding Airway Epithelial Potassium Channels Is Associated with Chronic Rhinosinusitis in a Pediatric Population
por: Purkey, Michael T., et al.
Publicado: (2014)

ParseCNV integrative copy number variation association software with quality tracking
por: Glessner, Joseph T., et al.
Publicado: (2013)

Genome-wide association study reveals two loci for serum magnesium concentrations in European-American children
por: Chang, Xiao, et al.
Publicado: (2015)

The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism
por: Hadley, Dexter, et al.
Publicado: (2014)

Molecular diagnosis and novel genes and phenotypes in a pediatric thoracic insufficiency cohort
por: Strong, Alanna, et al.
Publicado: (2023)

Gene Network Analysis in a Pediatric Cohort Identifies Novel Lung Function Genes
por: Ong, Bruce A., et al.
Publicado: (2013)

GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus
por: Sleiman, Patrick, et al.
Publicado: (2013)

Duplication of the SLIT3 Locus on 5q35.1 Predisposes to Major Depressive Disorder
por: Glessner, Joseph T., et al.
Publicado: (2010)

Ciliopathies: Coloring outside of the lines
por: Strong, Alanna, et al.
Publicado: (2020)

MONTAGE: a new tool for high-throughput detection of mosaic copy number variation
por: Glessner, Joseph T., et al.
Publicado: (2021)

The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature
por: Zhao, Jianhua, et al.
Publicado: (2010)

Single Cell Transcriptome Analysis of Peripheral Blood Mononuclear Cells in Freshly Isolated versus Stored Blood Samples
por: Qu, Hui-Qi, et al.
Publicado: (2023)

A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci
por: Bradfield, Jonathan P., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_0urfcrtqpsnbabjp4hr94kqhem