Cargando…

CSF1R as a Therapeutic Target in Bone Diseases: Obvious but Not so Simple

PURPOSE OF REVIEW: The purpose of the review is to summarize the expression and function of CSF1R and its ligands in bone homeostasis and constraints on therapeutic targeting of this axis. RECENT FINDINGS: Bone development and homeostasis depends upon interactions between mesenchymal cells and cells...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hume, David A., Batoon, Lena, Sehgal, Anuj, Keshvari, Sahar, Irvine, Katharine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Osteoimmunology (A Pettit and J Charles, Section Editors)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718875/ https://www.ncbi.nlm.nih.gov/pubmed/36197652 http://dx.doi.org/10.1007/s11914-022-00757-4

Ejemplares similares

Inflammasomes and the IL-1 Family in Bone Homeostasis and Disease
por: Tseng, Hsu-Wen, et al.
Publicado: (2022)

Vitamin D Regulation of Immune Function
por: Bikle, Daniel D
Publicado: (2022)

Osteoclast Recycling and the Rebound Phenomenon Following Denosumab Discontinuation
por: Kim, Albert S., et al.
Publicado: (2022)

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation
por: Keshvari, Sahar, et al.
Publicado: (2021)

Straight roads into nowhere – obvious and not-so-obvious biological models for ferrophobic surfaces
por: Konrad, Wilfried, et al.
Publicado: (2022)

Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations
por: Patkar, Omkar L., et al.
Publicado: (2021)

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling
por: Stables, Jennifer, et al.
Publicado: (2022)

Risk Assessment of Micronutrients Deficiency in Vegetarian or Vegan Children: Not So Obvious
por: Chouraqui, Jean-Pierre
Publicado: (2023)

Autoimmune Inflammation and Insulin Resistance: Hallmarks So Far and Yet So Close to Explain Diabetes Endotypes
por: Petrelli, Alessandra, et al.
Publicado: (2021)

Not so simple renal cysts
por: Brodin-Sartorius, Albane, et al.
Publicado: (2010)

A Long, Happy, Healthy but Uncomfortable Life?
Publicado: (1999)

Should You Complete Your Course of Antibiotics?
Publicado: (1999)

Should Everyone Expect to Be a Top Chap?
Publicado: (1999)

The Management of Cancer Timing and the Two Week Rule
Publicado: (2000)

Postcode or National (World) Governance, and the Art of Medicine
Publicado: (2000)

Do We Need a Real Health Service?
Publicado: (2000)

Public Health: Beware the Lobby and Listen to the Generalist
por: Coemgenus,
Publicado: (2000)

Communication and Complaints
Publicado: (1999)

Clinical Governance: Expect Not the Best but the Ideal
Publicado: (1999)

Money Is Only a Small Part of the Answer
Publicado: (2000)

The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche
por: Sehgal, Anuj, et al.
Publicado: (2018)

Cell Sources for Human In vitro Bone Models
por: Ansari, Sana, et al.
Publicado: (2021)

Is There a Governing Role of Osteocytes in Bone Tissue Regeneration?
por: Cao, Wei, et al.
Publicado: (2020)

New Microbiological Techniques for the Diagnosis of Bacterial Infections and Sepsis in ICU Including Point of Care
por: Peri, Anna Maria, et al.
Publicado: (2021)

A Simple Protocol to Effectively Manage Anal Fistulas with No Obvious Internal Opening
por: Garg, Pankaj, et al.
Publicado: (2021)

Aging and Mechanoadaptive Responsiveness of Bone
por: Javaheri, Behzad, et al.
Publicado: (2019)

Acute breathlessness with frank hemoptysis following catheter ablation for atrial fibrillation, a cause not so obvious
por: Waddingham, Peter Henry, et al.
Publicado: (2019)

Cross Talk Between Macrophages and Cancer Cells in the Bone Metastatic Environment
por: Batoon, Lena, et al.
Publicado: (2021)

How and why? Technology and practices used by university mathematics lecturers for emergency remote teaching during the COVID-19 pandemic
por: Ní Fhloinn, Eabhnat, et al.
Publicado: (2021)

The student perspective on teaching and assessment during initial COVID-19 related closures at Irish universities: implications for the future
por: Hyland, Diarmaid, et al.
Publicado: (2021)

Mathematics and statistics distance learning: more than just online teaching
por: Hilliam, Rachel, et al.
Publicado: (2021)

Flexible learner or imposter? Learning A Level mathematics in England through the COVID-19 pandemic
por: Golding, Jennie
Publicado: (2021)

Severe heparin-induced thrombocytopenia: when the obvious is not obvious, a case report
por: Cormack, Graham M, et al.
Publicado: (2007)

Weight Management in Patients with Type 2 Diabetes: a Multidisciplinary Real-world Approach
por: Hamdy, Osama, et al.
Publicado: (2018)

Towards a Connectomic Description of the Osteocyte Lacunocanalicular Network in Bone
por: Weinkamer, Richard, et al.
Publicado: (2019)

Clinical Management of Hypertriglyceridemia in the Prevention of Cardiovascular Disease and Pancreatitis
por: Hernandez, Patricia, et al.
Publicado: (2021)

Phytosterols and Cardiovascular Disease
por: Makhmudova, Umidakhon, et al.
Publicado: (2021)

Moving the Needle on Atherosclerotic Cardiovascular Disease and Heart Failure with Influenza Vaccination
por: Behrouzi, Bahar, et al.
Publicado: (2021)

The SMYD family proteins in immunology: An update of their obvious and non-obvious relations with the immune system
por: Rubio-Tomás, Teresa
Publicado: (2021)

Bilateral Integrative Medicine, Obviously
por: Stumpf, Steven H., et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_vcngpil25cd9vmp6ngs4jeh090