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Cardiac amyloidosis—An underdiagnosed cause of heart failure: A case report and review of literature

Restrictive cardiomyopathy secondary to cardiac amyloidosis is an underdiagnosed, but treatable, cause of heart failure involving an extracellular deposition of misfolded protein. Hereby, we report a case of a female patient with history of nephrotic syndrome for 1 year who subsequently presented wi...

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Autores principales: Parmar, Kanak, Benjanuwattra, Juthipong, Sethi, Pooja, Tijani, Lukman, Hurst, Philip, Pertuz, Gaspar Del‐Rio, Argueta‐Sosa, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718913/
https://www.ncbi.nlm.nih.gov/pubmed/36478969
http://dx.doi.org/10.1002/ccr3.6525
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author Parmar, Kanak
Benjanuwattra, Juthipong
Sethi, Pooja
Tijani, Lukman
Hurst, Philip
Pertuz, Gaspar Del‐Rio
Argueta‐Sosa, Erwin
author_facet Parmar, Kanak
Benjanuwattra, Juthipong
Sethi, Pooja
Tijani, Lukman
Hurst, Philip
Pertuz, Gaspar Del‐Rio
Argueta‐Sosa, Erwin
author_sort Parmar, Kanak
collection PubMed
description Restrictive cardiomyopathy secondary to cardiac amyloidosis is an underdiagnosed, but treatable, cause of heart failure involving an extracellular deposition of misfolded protein. Hereby, we report a case of a female patient with history of nephrotic syndrome for 1 year who subsequently presented with symptoms of heart failure. The findings on cardiac imaging supported the suspicion of cardiac amyloidosis. Further laboratory workup for amyloidosis was pursued along with endomyocardial biopsy which confirmed amyloidosis‐AL type. Patient was started on chemotherapy. The case underscores the importance of a timely diagnosis with the help of symptomatology and imaging along with a multidisciplinary approach for patient care.
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spelling pubmed-97189132022-12-06 Cardiac amyloidosis—An underdiagnosed cause of heart failure: A case report and review of literature Parmar, Kanak Benjanuwattra, Juthipong Sethi, Pooja Tijani, Lukman Hurst, Philip Pertuz, Gaspar Del‐Rio Argueta‐Sosa, Erwin Clin Case Rep Case Report Restrictive cardiomyopathy secondary to cardiac amyloidosis is an underdiagnosed, but treatable, cause of heart failure involving an extracellular deposition of misfolded protein. Hereby, we report a case of a female patient with history of nephrotic syndrome for 1 year who subsequently presented with symptoms of heart failure. The findings on cardiac imaging supported the suspicion of cardiac amyloidosis. Further laboratory workup for amyloidosis was pursued along with endomyocardial biopsy which confirmed amyloidosis‐AL type. Patient was started on chemotherapy. The case underscores the importance of a timely diagnosis with the help of symptomatology and imaging along with a multidisciplinary approach for patient care. John Wiley and Sons Inc. 2022-12-02 /pmc/articles/PMC9718913/ /pubmed/36478969 http://dx.doi.org/10.1002/ccr3.6525 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Parmar, Kanak
Benjanuwattra, Juthipong
Sethi, Pooja
Tijani, Lukman
Hurst, Philip
Pertuz, Gaspar Del‐Rio
Argueta‐Sosa, Erwin
Cardiac amyloidosis—An underdiagnosed cause of heart failure: A case report and review of literature
title Cardiac amyloidosis—An underdiagnosed cause of heart failure: A case report and review of literature
title_full Cardiac amyloidosis—An underdiagnosed cause of heart failure: A case report and review of literature
title_fullStr Cardiac amyloidosis—An underdiagnosed cause of heart failure: A case report and review of literature
title_full_unstemmed Cardiac amyloidosis—An underdiagnosed cause of heart failure: A case report and review of literature
title_short Cardiac amyloidosis—An underdiagnosed cause of heart failure: A case report and review of literature
title_sort cardiac amyloidosis—an underdiagnosed cause of heart failure: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718913/
https://www.ncbi.nlm.nih.gov/pubmed/36478969
http://dx.doi.org/10.1002/ccr3.6525
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