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The BE (2)-M17 cell line has a better dopaminergic phenotype than the traditionally used for Parkinson´s research SH-SY5Y, which is mostly serotonergic

SH-SY5Y is a cell line derived from human neuroblastoma. It is one of the most widely used in vitro models to study Parkinson’s disease. Surprisingly, it has been found that it does not develop a dopaminergic phenotype after differentiation, questioning its usefulness as a Parkinson’s model. There a...

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Detalles Bibliográficos
Autores principales: Carvajal-Oliveros, Angel, Uriostegui-Arcos, Maritere, Zurita, Mario, Melchy-Perez, Erika I., Narváez-Padilla, Verónica, Reynaud, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718961/
https://www.ncbi.nlm.nih.gov/pubmed/36471713
http://dx.doi.org/10.1016/j.ibneur.2022.11.007

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