Cargando…
The BE (2)-M17 cell line has a better dopaminergic phenotype than the traditionally used for Parkinson´s research SH-SY5Y, which is mostly serotonergic
SH-SY5Y is a cell line derived from human neuroblastoma. It is one of the most widely used in vitro models to study Parkinson’s disease. Surprisingly, it has been found that it does not develop a dopaminergic phenotype after differentiation, questioning its usefulness as a Parkinson’s model. There a...
Autores principales: | Carvajal-Oliveros, Angel, Uriostegui-Arcos, Maritere, Zurita, Mario, Melchy-Perez, Erika I., Narváez-Padilla, Verónica, Reynaud, Enrique |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718961/ https://www.ncbi.nlm.nih.gov/pubmed/36471713 http://dx.doi.org/10.1016/j.ibneur.2022.11.007 |
Ejemplares similares
-
Disruption of TFIIH activities generates a stress gene expression response and reveals possible new targets against cancer
por: Uriostegui-Arcos, Maritere, et al.
Publicado: (2020) -
Parkinsonian phenotypes induced by Synphilin-1 expression are differentially contributed by serotonergic and dopaminergic circuits and suppressed by nicotine treatment
por: Carvajal-Oliveros, Angel, et al.
Publicado: (2023) -
Heterochromatin Reduction Correlates with the Increase of the KDM4B and KDM6A Demethylases and the Expression of Pericentromeric DNA during the Acquisition of a Transformed Phenotype
por: Gurrion, Cinthya, et al.
Publicado: (2017) -
Splicing activates transcription from weak promoters upstream of alternative exons
por: Uriostegui-Arcos, Maritere, et al.
Publicado: (2023) -
Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism
por: Song, Ju-Xian, et al.
Publicado: (2012)