A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes

BACKGROUND: Stress responses within the β cell have been linked with both increased β cell death and accelerated immune activation in type 1 diabetes (T1D). At present, information on the timing and scope of these responses as well as disease-related changes in islet β cell protein expression during...

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Detalles Bibliográficos
Autores principales: Syed, Farooq, Singhal, Divya, Raedschelders, Koen, Krishnan, Preethi, Bone, Robert N., McLaughlin, Madeline R., Van Eyk, Jennifer E., Mirmira, Raghavendra G., Yang, Mei-Ling, Mamula, Mark J., Wu, Huanmei, Liu, Xiaowen, Evans-Molina, Carmella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719098/
https://www.ncbi.nlm.nih.gov/pubmed/36463755
http://dx.doi.org/10.1016/j.ebiom.2022.104379

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