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Estrogen antagonizes ASIC1a-induced chondrocyte mitochondrial stress in rheumatoid arthritis

BACKGROUND: Destruction of articular cartilage and bone is the main cause of joint dysfunction in rheumatoid arthritis (RA). Acid-sensing ion channel 1a (ASIC1a) is a key molecule that mediates the destruction of RA articular cartilage. Estrogen has been proven to have a protective effect against ar...

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Detalles Bibliográficos
Autores principales:	Zai, Zhuoyan, Xu, Yayun, Qian, Xuewen, Li, Zihan, Ou, Ziyao, Zhang, Tao, Wang, Longfei, Ling, Yian, Peng, Xiaoqing, Zhang, Yihao, Chen, Feihu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719153/ https://www.ncbi.nlm.nih.gov/pubmed/36463203 http://dx.doi.org/10.1186/s12967-022-03781-1

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