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Exenatide regulates Th17/Treg balance via PI3K/Akt/FoxO1 pathway in db/db mice

BACKGROUND: The T helper 17 (Th17)/T regulatory (Treg) cell imbalance is involved in the course of obesity and type 2 diabetes mellitus (T2DM). In the current study, the exact role of glucagon-like peptide-1 receptor agonist (GLP-1RA) exenatide on regulating the Th17/Treg balance and the underlying...

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Detalles Bibliográficos
Autores principales:	Xu, Qinqin, Zhang, Xiaoling, Li, Tao, Shao, Shiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719171/ https://www.ncbi.nlm.nih.gov/pubmed/36463128 http://dx.doi.org/10.1186/s10020-022-00574-6

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