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Monocytes educated by cancer-associated fibroblasts secrete exosomal miR-181a to activate AKT signaling in breast cancer cells

BACKGROUND: Cancer-associated fibroblasts (CAFs), one of the major components of the tumor stroma, contribute to an immunosuppressive tumor microenvironment (TME) through the induction and functional polarization of protumoral macrophages. We have herein investigated the contribution of CAFs to mono...

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Detalles Bibliográficos
Autores principales:	Pakravan, Katayoon, Mossahebi-Mohammadi, Majid, Ghazimoradi, Mohammad H., Cho, William C., Sadeghizadeh, Majid, Babashah, Sadegh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719191/ https://www.ncbi.nlm.nih.gov/pubmed/36463188 http://dx.doi.org/10.1186/s12967-022-03780-2

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