Role of Uric Acid Levels in the Development of Gestational Diabetes Mellitus: A Review

Gestational diabetes mellitus (GDM) is a common disorder affecting pregnancy. Besides conventional risk factors, several novel risk factors have been linked to causing GDM. Increased serum uric acid levels, also termed hyperuricemia, are regarded as one of the significant risk factors for increased...

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Autores principales: Khan, Farhana Yaqoob, Kauser, Humaira, Palakeel, Jaimee J, Ali, Mazin, Chhabra, Sanika, Lamsal Lamichhane, Smriti, Opara, Collins O, Hanif, Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Endocrinology/Diabetes/Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719288/
https://www.ncbi.nlm.nih.gov/pubmed/36475181
http://dx.doi.org/10.7759/cureus.31057
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author Khan, Farhana Yaqoob
Kauser, Humaira
Palakeel, Jaimee J
Ali, Mazin
Chhabra, Sanika
Lamsal Lamichhane, Smriti
Opara, Collins O
Hanif, Asif
author_facet Khan, Farhana Yaqoob
Kauser, Humaira
Palakeel, Jaimee J
Ali, Mazin
Chhabra, Sanika
Lamsal Lamichhane, Smriti
Opara, Collins O
Hanif, Asif
author_sort Khan, Farhana Yaqoob
collection PubMed
description Gestational diabetes mellitus (GDM) is a common disorder affecting pregnancy. Besides conventional risk factors, several novel risk factors have been linked to causing GDM. Increased serum uric acid levels, also termed hyperuricemia, are regarded as one of the significant risk factors for increased insulin resistance and GDM, causing detrimental impacts on both mother and child. The likelihood of developing GDM is at its peak during the first three months of pregnancy in patients with hyperuricemia. Still, its pathophysiology needs to be evaluated in detail. This review is aimed at assessing the function of hyperuricemia in the development of GDM.
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spelling pubmed-97192882022-12-05 Role of Uric Acid Levels in the Development of Gestational Diabetes Mellitus: A Review Khan, Farhana Yaqoob Kauser, Humaira Palakeel, Jaimee J Ali, Mazin Chhabra, Sanika Lamsal Lamichhane, Smriti Opara, Collins O Hanif, Asif Cureus Endocrinology/Diabetes/Metabolism Gestational diabetes mellitus (GDM) is a common disorder affecting pregnancy. Besides conventional risk factors, several novel risk factors have been linked to causing GDM. Increased serum uric acid levels, also termed hyperuricemia, are regarded as one of the significant risk factors for increased insulin resistance and GDM, causing detrimental impacts on both mother and child. The likelihood of developing GDM is at its peak during the first three months of pregnancy in patients with hyperuricemia. Still, its pathophysiology needs to be evaluated in detail. This review is aimed at assessing the function of hyperuricemia in the development of GDM. Cureus 2022-11-03 /pmc/articles/PMC9719288/ /pubmed/36475181 http://dx.doi.org/10.7759/cureus.31057 Text en Copyright © 2022, Khan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Khan, Farhana Yaqoob
Kauser, Humaira
Palakeel, Jaimee J
Ali, Mazin
Chhabra, Sanika
Lamsal Lamichhane, Smriti
Opara, Collins O
Hanif, Asif
Role of Uric Acid Levels in the Development of Gestational Diabetes Mellitus: A Review
title Role of Uric Acid Levels in the Development of Gestational Diabetes Mellitus: A Review
title_full Role of Uric Acid Levels in the Development of Gestational Diabetes Mellitus: A Review
title_fullStr Role of Uric Acid Levels in the Development of Gestational Diabetes Mellitus: A Review
title_full_unstemmed Role of Uric Acid Levels in the Development of Gestational Diabetes Mellitus: A Review
title_short Role of Uric Acid Levels in the Development of Gestational Diabetes Mellitus: A Review
title_sort role of uric acid levels in the development of gestational diabetes mellitus: a review
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719288/
https://www.ncbi.nlm.nih.gov/pubmed/36475181
http://dx.doi.org/10.7759/cureus.31057
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