IL-1 TERT PROMOTER C228T MUTATION IN NEURAL PROGENITORS CONFERS GROWTH ADVANTAGE FOLLOWING TELOMERE SHORTENING IN VIVO

Heterozygous TERT (Telomerase reverse transcriptase) promoter mutations (TPMs) facilitate TERT expression and are the most frequent mutation in glioblastoma (GBM). A recent analysis revealed this mutation is one of the earliest events in gliomagenesis, however no appropriate human models have been e...

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Detalles Bibliográficos
Autores principales: Furnari, Frank, Miki, Shunichiro, Koga, Tomoyuki, Mckinney, Andrew M, Parisian, Alison D, Tadokoro, Takahiro, Vadla, Raghavendra, Masala, Martin, Hevner, Robert F, Costello, Joseph F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719355/
http://dx.doi.org/10.1093/noajnl/vdac167.110

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