Cargando…

Germline PRDM1 Variant rs2185379 in Long-Term Recurrence-Free Survivors of Advanced Ovarian Cancer

PURPOSE: To identify the germline genetic characteristics of long-term recurrence-free survivors that can be applied to establishing a new strategy for curing advanced cancer, we investigated the whole-genome single nucleotide variants of ovarian cancer patients. PATIENTS AND METHODS: DNA specimens...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mitamura, Takashi, Zhai, Tianyue, Hatanaka, Kanako C, Hatanaka, Yutaka, Amano, Toraji, Wang, Lei, Tanaka, Shinya, Watari, Hidemichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719363/ https://www.ncbi.nlm.nih.gov/pubmed/36471864 http://dx.doi.org/10.2147/PGPM.S387120

Ejemplares similares

Genetic heterogeneity during breast cancer progression in young patients
por: Hagio, Kanako, et al.
Publicado: (2021)

Combination therapy with bevacizumab and a CCR2 inhibitor for human ovarian cancer: An in vivo validation study
por: Zhai, Tianyue, et al.
Publicado: (2023)

The prognosis of endometrial cancers stratified with conventional risk factors and modified molecular classification
por: Yamazaki, Hiroyuki, et al.
Publicado: (2022)

Clusterin is a potential molecular predictor for ovarian cancer patient's survival: targeting Clusterin improves response to paclitaxel
por: Hassan, Mohamed K, et al.
Publicado: (2011)

Assessment for the timing of comprehensive genomic profiling tests in patients with advanced solid cancers
por: Hagio, Kanako, et al.
Publicado: (2023)

Bortezomib depended on PRDM1 and TP53 to exert therapeutic effect in activated B-cell-like diffuse large B-cell lymphoma
por: Tang, Jing, et al.
Publicado: (2023)

Expression patterns of prdm1 during chicken embryonic and germline development
por: Wan, Zhiyi, et al.
Publicado: (2014)

Absence of Germline CHK2 Mutations in Familial Gastric Cancer
por: Kimura, Kenji, et al.
Publicado: (2000)

P18/Stathmin1 is regulated by miR-31 in ovarian cancer in response to taxane
por: Hassan, Mohamed Kamel, et al.
Publicado: (2015)

Germline Mutations of the PTEN/MMAC1 Gene in Japanese Patients with Cowden Disease
por: Kohno, Takashi, et al.
Publicado: (1998)

VEGFR1-tyrosine kinase signaling in pulmonary fibrosis
por: Amano, Hideki, et al.
Publicado: (2021)

Germline Mutations of the MEN1 Gene in Japanese Kindred with Multiple Endocrine Neoplasia Type 1
por: Shimizu, Satoko, et al.
Publicado: (1997)

Two novel and one known pathogenic germline mutations in MMRs in Chinese families with Lynch syndrome
por: Li, Juyi, et al.
Publicado: (2021)

The blended phenotype of a germline RIT1 and a mosaic PIK3CA variant
por: Berland, Siren, et al.
Publicado: (2021)

Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes
por: Forte, Giovanna, et al.
Publicado: (2022)

PIK3CA mutation, reduced AKT serine 473 phosphorylation, and increased ERα serine 167 phosphorylation are positive prognostic indicators in postmenopausal estrogen receptor-positive early breast cancer
por: Ishida, Naoko, et al.
Publicado: (2018)

Comparison analysis of multiple-omics data between female germline stem cells and spermatogonial stem cells
por: Tian, Geng G., et al.
Publicado: (2022)

Characterization of somatic mutations of colorectal tumor in a patient with concurrent APC and MLH1 germline mutations
por: Cheng, Yunsheng, et al.
Publicado: (2023)

Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats
por: Kobayashi, Toshihiro, et al.
Publicado: (2021)

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation
por: Grabole, Nils, et al.
Publicado: (2013)

Lack of evidence for germline WWP1 pathogenic variants in gastrointestinal polyposis and other phenotypes suggestive of PTEN-hamartoma-tumor syndrome
por: Gonzalez-Abuin, Noemi, et al.
Publicado: (2023)

High level expression of AMAP1 protein correlates with poor prognosis and survival after surgery of head and neck squamous cell carcinoma patients
por: Sato, Hiroki, et al.
Publicado: (2014)

Association of PRDM16 rs12409277 and CtBP2 rs1561589 gene polymorphisms with lipid profile of adolescents
por: Maksimovic, Nela, et al.
Publicado: (2021)

microRNA 31 functions as an endometrial cancer oncogene by suppressing Hippo tumor suppressor pathway
por: Mitamura, Takashi, et al.
Publicado: (2014)

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation
por: Gell, Joanna J., et al.
Publicado: (2018)

p53 accumulation is a strong predictor of recurrence in estrogen receptor-positive breast cancer patients treated with aromatase inhibitors
por: Yamamoto, Mitsugu, et al.
Publicado: (2014)

Adenomatous polyposis coli-binding protein end-binding 1 promotes hepatocellular carcinoma growth and metastasis
por: Aiyama, Takeshi, et al.
Publicado: (2020)

miR-363 confers taxane resistance in ovarian cancer by targeting the Hippo pathway member, LATS2
por: Mohamed, Zeinab, et al.
Publicado: (2018)

Predicting the Efficacy and Safety of TACTICs (Tumor Angiogenesis-Specific CAR-T Cells Impacting Cancers) Therapy for Soft Tissue Sarcoma Patients
por: Fujiwara, Kento, et al.
Publicado: (2020)

Targeting BMI1 mitigates chemoresistance in ovarian cancer
por: Dey, Anindya, et al.
Publicado: (2022)

A Case of C5 Vertebral Chordoma in a 73-Year-Old Patient with More Than 8 Years of Follow-Up after Total Piecemeal Spondylectomy
por: Tanaka, Keigo, et al.
Publicado: (2017)

Two Germline Missense Mutations at Codons 804 and 806 of the RET Proto‐oncogene in the Same Allele in a Patient with Multiple Endocrine Neoplasia Type 2B without Codon 918 Mutation
por: Miyauchi, Akira, et al.
Publicado: (1999)

The disease sites of female genital cancers of BRCA1/2-associated hereditary breast and ovarian cancer: a retrospective study
por: Mitamura, Takashi, et al.
Publicado: (2021)

Lymphadenectomy can be omitted for low-risk endometrial cancer based on preoperative assessments
por: Mitamura, Takashi, et al.
Publicado: (2014)

Enhanced Angiogenesis in Salivary Duct Carcinoma Ex-Pleomorphic Adenoma
por: Suzuki, Takayoshi, et al.
Publicado: (2021)

Clinical Relevance of Estrogen Reactivity in the Breast Cancer Microenvironment
por: Takeshita, Takashi, et al.
Publicado: (2022)

Germline BRCA2 mutations detected in pediatric sequencing studies impact parents’ evaluation and care
por: Walsh, Michael F., et al.
Publicado: (2017)

A germline PALB2 pathogenic variant identified in a pediatric high-grade glioma
por: Zhong, Yiming, et al.
Publicado: (2020)

Cardiac Rehabilitation With Dynamic Exercise Increases the Number of Muse Cells in the Peripheral Blood of Patients With Heart Disease
por: Minatoguchi, Shingo, et al.
Publicado: (2018)

Parathyroid Tumors in Atomic Bomb Survivors in Hiroshima: Epidemiological Study from Registered Cases at Hiroshima Prefecture Tumor Tissue Registry, 1974‐1987
por: Takeichi, Nobuo, et al.
Publicado: (1991)

Cannot write session to /tmp/vufind_sessions/sess_26odv0ah0dlcv1c5q814mlv8pl