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Genetic features and therapeutic relevance of emergent circulating tumor DNA alterations in refractory non-colorectal gastrointestinal cancers

Acquired resistance to systemic treatments is inevitable in most cancers, but the genetic basis for this in many cancer types has remained elusive due to constraints in obtaining tissue specimens longitudinally. In the management of gastrointestinal cancers, molecular profiling is conventionally per...

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Detalles Bibliográficos
Autores principales: Hsiehchen, David, Bucheit, Leslie, Yang, Dong, Beg, Muhammad Shaalan, Lim, Mir, Lee, Sunyoung S., Kasi, Pashtoon Murtaza, Kaseb, Ahmed O., Zhu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719461/
https://www.ncbi.nlm.nih.gov/pubmed/36463294
http://dx.doi.org/10.1038/s41467-022-35144-1