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Genetic features and therapeutic relevance of emergent circulating tumor DNA alterations in refractory non-colorectal gastrointestinal cancers
Acquired resistance to systemic treatments is inevitable in most cancers, but the genetic basis for this in many cancer types has remained elusive due to constraints in obtaining tissue specimens longitudinally. In the management of gastrointestinal cancers, molecular profiling is conventionally per...
Autores principales: | Hsiehchen, David, Bucheit, Leslie, Yang, Dong, Beg, Muhammad Shaalan, Lim, Mir, Lee, Sunyoung S., Kasi, Pashtoon Murtaza, Kaseb, Ahmed O., Zhu, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719461/ https://www.ncbi.nlm.nih.gov/pubmed/36463294 http://dx.doi.org/10.1038/s41467-022-35144-1 |
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