Single-molecule characterization of subtype-specific β1 integrin mechanics

Although integrins are known to be mechanosensitive and to possess many subtypes that have distinct physiological roles, single molecule studies of force exertion have thus far been limited to RGD-binding integrins. Here, we show that integrin α4β1 and RGD-binding integrins (αVβ1 and α5β1) require m...

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Detalles Bibliográficos
Autores principales: Jo, Myung Hyun, Li, Jing, Jaumouillé, Valentin, Hao, Yuxin, Coppola, Jessica, Yan, Jiabin, Waterman, Clare M., Springer, Timothy A., Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719539/
https://www.ncbi.nlm.nih.gov/pubmed/36463259
http://dx.doi.org/10.1038/s41467-022-35173-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719539/
https://www.ncbi.nlm.nih.gov/pubmed/36463259
http://dx.doi.org/10.1038/s41467-022-35173-w

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