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Clinical Characteristics and Prognosis Analysis of Acinetobacter baumannii Bloodstream Infection Based on Propensity Matching

PURPOSE: In view of the fact that Acinetobacter baumannii bloodstream infection(BSI) is a great threat to human survival, early identification of the risk factors affecting prognosis will be of great benefit to the clinic. PATIENTS AND METHODS: A propensity score matching method was used to collect...

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Autores principales: Wang, Jinghui, Zhang, Jun, Wu, Zhuang-hao, Liu, Lei, Ma, Zijun, Lai, Cheng-cheng, Luo, Yong-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719707/
https://www.ncbi.nlm.nih.gov/pubmed/36474906
http://dx.doi.org/10.2147/IDR.S387898
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author Wang, Jinghui
Zhang, Jun
Wu, Zhuang-hao
Liu, Lei
Ma, Zijun
Lai, Cheng-cheng
Luo, Yong-gang
author_facet Wang, Jinghui
Zhang, Jun
Wu, Zhuang-hao
Liu, Lei
Ma, Zijun
Lai, Cheng-cheng
Luo, Yong-gang
author_sort Wang, Jinghui
collection PubMed
description PURPOSE: In view of the fact that Acinetobacter baumannii bloodstream infection(BSI) is a great threat to human survival, early identification of the risk factors affecting prognosis will be of great benefit to the clinic. PATIENTS AND METHODS: A propensity score matching method was used to collect patients identified with Acinetobacter baumannii BSI from 2016 to 2020 from a reputable hospital in China. RESULTS: A total of 398 patients were considered. According to the 28-day prognosis, they were divided into the survival group 150 (37.7%) and the death group 248 (62.3%), and the prognosis was analyzed. Subsequently, Propensity score matching was adjusted for variables with p-values <O.2 in the baseline data, equalized differences in baseline, multivariate paired logistics regression analysis was performed on 63 matched patients and showed that patients with Acinetobacter baumannii BSI who had higher SOFA scores at the time of infection, with septic shock, or mechanical ventilation were more likely to be fatally hit within 28 days and had a poor prognosis. CONCLUSION: The existence of drug resistance with Acinetobacter baumannii only leads to Inappropriate empirical antibiotic therapy, ultimately, Inappropriate empirical antibiotic therapy was the direct predictor of mortality.
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spelling pubmed-97197072022-12-05 Clinical Characteristics and Prognosis Analysis of Acinetobacter baumannii Bloodstream Infection Based on Propensity Matching Wang, Jinghui Zhang, Jun Wu, Zhuang-hao Liu, Lei Ma, Zijun Lai, Cheng-cheng Luo, Yong-gang Infect Drug Resist Original Research PURPOSE: In view of the fact that Acinetobacter baumannii bloodstream infection(BSI) is a great threat to human survival, early identification of the risk factors affecting prognosis will be of great benefit to the clinic. PATIENTS AND METHODS: A propensity score matching method was used to collect patients identified with Acinetobacter baumannii BSI from 2016 to 2020 from a reputable hospital in China. RESULTS: A total of 398 patients were considered. According to the 28-day prognosis, they were divided into the survival group 150 (37.7%) and the death group 248 (62.3%), and the prognosis was analyzed. Subsequently, Propensity score matching was adjusted for variables with p-values <O.2 in the baseline data, equalized differences in baseline, multivariate paired logistics regression analysis was performed on 63 matched patients and showed that patients with Acinetobacter baumannii BSI who had higher SOFA scores at the time of infection, with septic shock, or mechanical ventilation were more likely to be fatally hit within 28 days and had a poor prognosis. CONCLUSION: The existence of drug resistance with Acinetobacter baumannii only leads to Inappropriate empirical antibiotic therapy, ultimately, Inappropriate empirical antibiotic therapy was the direct predictor of mortality. Dove 2022-11-30 /pmc/articles/PMC9719707/ /pubmed/36474906 http://dx.doi.org/10.2147/IDR.S387898 Text en © 2022 Wang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Wang, Jinghui
Zhang, Jun
Wu, Zhuang-hao
Liu, Lei
Ma, Zijun
Lai, Cheng-cheng
Luo, Yong-gang
Clinical Characteristics and Prognosis Analysis of Acinetobacter baumannii Bloodstream Infection Based on Propensity Matching
title Clinical Characteristics and Prognosis Analysis of Acinetobacter baumannii Bloodstream Infection Based on Propensity Matching
title_full Clinical Characteristics and Prognosis Analysis of Acinetobacter baumannii Bloodstream Infection Based on Propensity Matching
title_fullStr Clinical Characteristics and Prognosis Analysis of Acinetobacter baumannii Bloodstream Infection Based on Propensity Matching
title_full_unstemmed Clinical Characteristics and Prognosis Analysis of Acinetobacter baumannii Bloodstream Infection Based on Propensity Matching
title_short Clinical Characteristics and Prognosis Analysis of Acinetobacter baumannii Bloodstream Infection Based on Propensity Matching
title_sort clinical characteristics and prognosis analysis of acinetobacter baumannii bloodstream infection based on propensity matching
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719707/
https://www.ncbi.nlm.nih.gov/pubmed/36474906
http://dx.doi.org/10.2147/IDR.S387898
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