Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions
We report two cases of primary hepatic mesothelial cysts in neonates previously identified during perinatal imaging. Both neonatal cases were reimaged in the postnatal period, demonstrating the persistence of these cystic hepatic lesions. In both instances, the decision was made to treat with surgic...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719715/ https://www.ncbi.nlm.nih.gov/pubmed/36475178 http://dx.doi.org/10.7759/cureus.31089 |
_version_ | 1784843387610857472 |
---|---|
author | Gosnell, Joseph M Dejesus, Jana Bigham, Lindsay Millian, Daniel Brondeel, Kimberley C Radhakrishnan, Ravi Stevenson, Heather L |
author_facet | Gosnell, Joseph M Dejesus, Jana Bigham, Lindsay Millian, Daniel Brondeel, Kimberley C Radhakrishnan, Ravi Stevenson, Heather L |
author_sort | Gosnell, Joseph M |
collection | PubMed |
description | We report two cases of primary hepatic mesothelial cysts in neonates previously identified during perinatal imaging. Both neonatal cases were reimaged in the postnatal period, demonstrating the persistence of these cystic hepatic lesions. In both instances, the decision was made to treat with surgical resection and both patients tolerated the surgery well with no significant postoperative complications. Histopathological examination of these lesions discovered a cuboidal lining that was calretinin and WT1 positive and CD31 negative, indicating the diagnosis of a mesothelial cyst of hepatic origin. These cases bring attention to the broad differential diagnosis of congenital primary hepatic cystic lesions, as well as the diagnostic pathway to confirm a primary hepatic mesothelial cyst. |
format | Online Article Text |
id | pubmed-9719715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-97197152022-12-05 Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions Gosnell, Joseph M Dejesus, Jana Bigham, Lindsay Millian, Daniel Brondeel, Kimberley C Radhakrishnan, Ravi Stevenson, Heather L Cureus Pathology We report two cases of primary hepatic mesothelial cysts in neonates previously identified during perinatal imaging. Both neonatal cases were reimaged in the postnatal period, demonstrating the persistence of these cystic hepatic lesions. In both instances, the decision was made to treat with surgical resection and both patients tolerated the surgery well with no significant postoperative complications. Histopathological examination of these lesions discovered a cuboidal lining that was calretinin and WT1 positive and CD31 negative, indicating the diagnosis of a mesothelial cyst of hepatic origin. These cases bring attention to the broad differential diagnosis of congenital primary hepatic cystic lesions, as well as the diagnostic pathway to confirm a primary hepatic mesothelial cyst. Cureus 2022-11-04 /pmc/articles/PMC9719715/ /pubmed/36475178 http://dx.doi.org/10.7759/cureus.31089 Text en Copyright © 2022, Gosnell et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Gosnell, Joseph M Dejesus, Jana Bigham, Lindsay Millian, Daniel Brondeel, Kimberley C Radhakrishnan, Ravi Stevenson, Heather L Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions |
title | Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions |
title_full | Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions |
title_fullStr | Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions |
title_full_unstemmed | Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions |
title_short | Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions |
title_sort | primary hepatic mesothelial cyst: a rare entity to be considered in the differential diagnosis of neonatal cystic lesions |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719715/ https://www.ncbi.nlm.nih.gov/pubmed/36475178 http://dx.doi.org/10.7759/cureus.31089 |
work_keys_str_mv | AT gosnelljosephm primaryhepaticmesothelialcystarareentitytobeconsideredinthedifferentialdiagnosisofneonatalcysticlesions AT dejesusjana primaryhepaticmesothelialcystarareentitytobeconsideredinthedifferentialdiagnosisofneonatalcysticlesions AT bighamlindsay primaryhepaticmesothelialcystarareentitytobeconsideredinthedifferentialdiagnosisofneonatalcysticlesions AT milliandaniel primaryhepaticmesothelialcystarareentitytobeconsideredinthedifferentialdiagnosisofneonatalcysticlesions AT brondeelkimberleyc primaryhepaticmesothelialcystarareentitytobeconsideredinthedifferentialdiagnosisofneonatalcysticlesions AT radhakrishnanravi primaryhepaticmesothelialcystarareentitytobeconsideredinthedifferentialdiagnosisofneonatalcysticlesions AT stevensonheatherl primaryhepaticmesothelialcystarareentitytobeconsideredinthedifferentialdiagnosisofneonatalcysticlesions |