Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions

We report two cases of primary hepatic mesothelial cysts in neonates previously identified during perinatal imaging. Both neonatal cases were reimaged in the postnatal period, demonstrating the persistence of these cystic hepatic lesions. In both instances, the decision was made to treat with surgic...

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Autores principales: Gosnell, Joseph M, Dejesus, Jana, Bigham, Lindsay, Millian, Daniel, Brondeel, Kimberley C, Radhakrishnan, Ravi, Stevenson, Heather L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719715/
https://www.ncbi.nlm.nih.gov/pubmed/36475178
http://dx.doi.org/10.7759/cureus.31089
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author Gosnell, Joseph M
Dejesus, Jana
Bigham, Lindsay
Millian, Daniel
Brondeel, Kimberley C
Radhakrishnan, Ravi
Stevenson, Heather L
author_facet Gosnell, Joseph M
Dejesus, Jana
Bigham, Lindsay
Millian, Daniel
Brondeel, Kimberley C
Radhakrishnan, Ravi
Stevenson, Heather L
author_sort Gosnell, Joseph M
collection PubMed
description We report two cases of primary hepatic mesothelial cysts in neonates previously identified during perinatal imaging. Both neonatal cases were reimaged in the postnatal period, demonstrating the persistence of these cystic hepatic lesions. In both instances, the decision was made to treat with surgical resection and both patients tolerated the surgery well with no significant postoperative complications. Histopathological examination of these lesions discovered a cuboidal lining that was calretinin and WT1 positive and CD31 negative, indicating the diagnosis of a mesothelial cyst of hepatic origin. These cases bring attention to the broad differential diagnosis of congenital primary hepatic cystic lesions, as well as the diagnostic pathway to confirm a primary hepatic mesothelial cyst.
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spelling pubmed-97197152022-12-05 Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions Gosnell, Joseph M Dejesus, Jana Bigham, Lindsay Millian, Daniel Brondeel, Kimberley C Radhakrishnan, Ravi Stevenson, Heather L Cureus Pathology We report two cases of primary hepatic mesothelial cysts in neonates previously identified during perinatal imaging. Both neonatal cases were reimaged in the postnatal period, demonstrating the persistence of these cystic hepatic lesions. In both instances, the decision was made to treat with surgical resection and both patients tolerated the surgery well with no significant postoperative complications. Histopathological examination of these lesions discovered a cuboidal lining that was calretinin and WT1 positive and CD31 negative, indicating the diagnosis of a mesothelial cyst of hepatic origin. These cases bring attention to the broad differential diagnosis of congenital primary hepatic cystic lesions, as well as the diagnostic pathway to confirm a primary hepatic mesothelial cyst. Cureus 2022-11-04 /pmc/articles/PMC9719715/ /pubmed/36475178 http://dx.doi.org/10.7759/cureus.31089 Text en Copyright © 2022, Gosnell et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Gosnell, Joseph M
Dejesus, Jana
Bigham, Lindsay
Millian, Daniel
Brondeel, Kimberley C
Radhakrishnan, Ravi
Stevenson, Heather L
Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions
title Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions
title_full Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions
title_fullStr Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions
title_full_unstemmed Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions
title_short Primary Hepatic Mesothelial Cyst: A Rare Entity to Be Considered in the Differential Diagnosis of Neonatal Cystic Lesions
title_sort primary hepatic mesothelial cyst: a rare entity to be considered in the differential diagnosis of neonatal cystic lesions
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719715/
https://www.ncbi.nlm.nih.gov/pubmed/36475178
http://dx.doi.org/10.7759/cureus.31089
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