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Repression of the iron exporter ferroportin may contribute to hepatocyte iron overload in individuals with type 2 diabetes

OBJECTIVE: Hyperferremia and hyperferritinemia are observed in patients and disease models of type 2 diabetes mellitus (T2DM). Likewise, patients with genetic iron overload diseases develop diabetes, suggesting a tight link between iron metabolism and diabetes. The liver controls systemic iron homeo...

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Detalles Bibliográficos
Autores principales:	Qiu, Ruiyue, Alikhanyan, Kristina, Volk, Nadine, Marques, Oriana, Mertens, Christina, Agarvas, Anand Ruban, Singh, Sanjana, Pepperkok, Rainer, Altamura, Sandro, Muckenthaler, Martina U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719871/ https://www.ncbi.nlm.nih.gov/pubmed/36436807 http://dx.doi.org/10.1016/j.molmet.2022.101644

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