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Twin Reversed Arterial Perfusion

Twin reversed arterial perfusion (TRAP) sequence is a rare condition found only in monochorionic pregnancies. It is a sequence in which a severely anomalous twin with an absent or rudimentary heart, also called an “acardiac twin,” is perfused by its co-twin. The cardiac system of this co-twin (pump...

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Detalles Bibliográficos
Autor principal: Hans, Punit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720044/
https://www.ncbi.nlm.nih.gov/pubmed/36475119
http://dx.doi.org/10.7759/cureus.31116
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author Hans, Punit
author_facet Hans, Punit
author_sort Hans, Punit
collection PubMed
description Twin reversed arterial perfusion (TRAP) sequence is a rare condition found only in monochorionic pregnancies. It is a sequence in which a severely anomalous twin with an absent or rudimentary heart, also called an “acardiac twin,” is perfused by its co-twin. The cardiac system of this co-twin (pump twin) provides circulatory support to the acardiac twin from as early as the first trimester. The exact pathogenesis of TRAP sequence is still unknown. However, the mere presence of vascular anastomoses in the placenta alone cannot lead to the development of TRAP sequence. Moreover, the presence of retrograde blood flow through arterio-arterial anastomoses increases the possibility of TRAP sequence diagnosis in a suspected monochorionic twin pregnancy. This report presents a case of TRAP sequence, which was undiagnosed till the delivery of twins. A 26-year-old patient gravida 3 para 2 (G3P2+0) with previous two normal deliveries, was referred to our emergency labor room at (assumed) 37 weeks of pregnancy, from a primary health center with complaints of vaginal leakage and a non-reassuring fetal status. She was immediately shifted to Operation Theatre and an emergency lower-segment cesarean section was performed. At the time of delivery, she was diagnosed as having a monochorionic diamniotic twin with TRAP sequence as one of the twins was acardiac, while the other was a live male baby (the pump twin) with massive ascites. A TRAP sequence pregnancy with a poor prognostic factor requires twin cord occlusion therapy or another form of intervention. Termination of the pregnancy is also an option, as it saves the patient from unnecessary obstetrical complications and morbidity.
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spelling pubmed-97200442022-12-05 Twin Reversed Arterial Perfusion Hans, Punit Cureus Obstetrics/Gynecology Twin reversed arterial perfusion (TRAP) sequence is a rare condition found only in monochorionic pregnancies. It is a sequence in which a severely anomalous twin with an absent or rudimentary heart, also called an “acardiac twin,” is perfused by its co-twin. The cardiac system of this co-twin (pump twin) provides circulatory support to the acardiac twin from as early as the first trimester. The exact pathogenesis of TRAP sequence is still unknown. However, the mere presence of vascular anastomoses in the placenta alone cannot lead to the development of TRAP sequence. Moreover, the presence of retrograde blood flow through arterio-arterial anastomoses increases the possibility of TRAP sequence diagnosis in a suspected monochorionic twin pregnancy. This report presents a case of TRAP sequence, which was undiagnosed till the delivery of twins. A 26-year-old patient gravida 3 para 2 (G3P2+0) with previous two normal deliveries, was referred to our emergency labor room at (assumed) 37 weeks of pregnancy, from a primary health center with complaints of vaginal leakage and a non-reassuring fetal status. She was immediately shifted to Operation Theatre and an emergency lower-segment cesarean section was performed. At the time of delivery, she was diagnosed as having a monochorionic diamniotic twin with TRAP sequence as one of the twins was acardiac, while the other was a live male baby (the pump twin) with massive ascites. A TRAP sequence pregnancy with a poor prognostic factor requires twin cord occlusion therapy or another form of intervention. Termination of the pregnancy is also an option, as it saves the patient from unnecessary obstetrical complications and morbidity. Cureus 2022-11-05 /pmc/articles/PMC9720044/ /pubmed/36475119 http://dx.doi.org/10.7759/cureus.31116 Text en Copyright © 2022, Hans et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Obstetrics/Gynecology
Hans, Punit
Twin Reversed Arterial Perfusion
title Twin Reversed Arterial Perfusion
title_full Twin Reversed Arterial Perfusion
title_fullStr Twin Reversed Arterial Perfusion
title_full_unstemmed Twin Reversed Arterial Perfusion
title_short Twin Reversed Arterial Perfusion
title_sort twin reversed arterial perfusion
topic Obstetrics/Gynecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720044/
https://www.ncbi.nlm.nih.gov/pubmed/36475119
http://dx.doi.org/10.7759/cureus.31116
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