Epigenetic-related gene mutations serve as potential biomarkers for immune checkpoint inhibitors in microsatellite-stable colorectal cancer

BACKGROUND: Combination therapy with immune checkpoint inhibitors (ICIs) may benefit approximately 10-20% of microsatellite-stable colorectal cancer (MSS-CRC) patients. However, there is a lack of optimal biomarkers. This study aims to understand the predictive value of epigenetic-related gene mutat...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Xiao, Huiting, Cui, Luying, Fang, Lin, Han, Shuling, Ruan, Yuli, Zhao, Wenyuan, Zhang, Yanqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720302/
https://www.ncbi.nlm.nih.gov/pubmed/36479108
http://dx.doi.org/10.3389/fimmu.2022.1039631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720302/
https://www.ncbi.nlm.nih.gov/pubmed/36479108
http://dx.doi.org/10.3389/fimmu.2022.1039631

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