Cargando…

Hemorrhagic Meningitis Due to Varicella-Zoster Virus: A Case Report With Clinical, Cytologic, and Radiologic Correlation

Although varicella-zoster virus (VZV) is known to affect the central nervous system in a protean manner, hemorrhagic VZV meningitis has not been well documented in the literature. Here, we correlate the clinical, cytologic, and radiologic findings in an immunocompromised patient presenting with suba...

Descripción completa

Detalles Bibliográficos
Autores principales: Gorolay, Vineet, Martens, David, Satgunaseelan, Laveniya, Van Camp, Louise, Winkler, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720349/
https://www.ncbi.nlm.nih.gov/pubmed/36479400
http://dx.doi.org/10.7759/cureus.31113
_version_ 1784843537904304128
author Gorolay, Vineet
Martens, David
Satgunaseelan, Laveniya
Van Camp, Louise
Winkler, Gemma
author_facet Gorolay, Vineet
Martens, David
Satgunaseelan, Laveniya
Van Camp, Louise
Winkler, Gemma
author_sort Gorolay, Vineet
collection PubMed
description Although varicella-zoster virus (VZV) is known to affect the central nervous system in a protean manner, hemorrhagic VZV meningitis has not been well documented in the literature. Here, we correlate the clinical, cytologic, and radiologic findings in an immunocompromised patient presenting with subarachnoid hemorrhage associated with VZV meningitis. Clinical findings included multidermatomal zoster, myelitis, and neurapraxia. Magnetic resonance imaging findings included superficial siderosis and diffused linear and nodular leptomeningeal enhancement. Cerebrospinal fluid cytology revealed hemorrhage and lymphocytic pleocytosis. This case report adds hemorrhagic meningitis to the spectrum of complications associated with disseminated VZV infection.
format Online
Article
Text
id pubmed-9720349
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-97203492022-12-06 Hemorrhagic Meningitis Due to Varicella-Zoster Virus: A Case Report With Clinical, Cytologic, and Radiologic Correlation Gorolay, Vineet Martens, David Satgunaseelan, Laveniya Van Camp, Louise Winkler, Gemma Cureus Pathology Although varicella-zoster virus (VZV) is known to affect the central nervous system in a protean manner, hemorrhagic VZV meningitis has not been well documented in the literature. Here, we correlate the clinical, cytologic, and radiologic findings in an immunocompromised patient presenting with subarachnoid hemorrhage associated with VZV meningitis. Clinical findings included multidermatomal zoster, myelitis, and neurapraxia. Magnetic resonance imaging findings included superficial siderosis and diffused linear and nodular leptomeningeal enhancement. Cerebrospinal fluid cytology revealed hemorrhage and lymphocytic pleocytosis. This case report adds hemorrhagic meningitis to the spectrum of complications associated with disseminated VZV infection. Cureus 2022-11-05 /pmc/articles/PMC9720349/ /pubmed/36479400 http://dx.doi.org/10.7759/cureus.31113 Text en Copyright © 2022, Gorolay et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Gorolay, Vineet
Martens, David
Satgunaseelan, Laveniya
Van Camp, Louise
Winkler, Gemma
Hemorrhagic Meningitis Due to Varicella-Zoster Virus: A Case Report With Clinical, Cytologic, and Radiologic Correlation
title Hemorrhagic Meningitis Due to Varicella-Zoster Virus: A Case Report With Clinical, Cytologic, and Radiologic Correlation
title_full Hemorrhagic Meningitis Due to Varicella-Zoster Virus: A Case Report With Clinical, Cytologic, and Radiologic Correlation
title_fullStr Hemorrhagic Meningitis Due to Varicella-Zoster Virus: A Case Report With Clinical, Cytologic, and Radiologic Correlation
title_full_unstemmed Hemorrhagic Meningitis Due to Varicella-Zoster Virus: A Case Report With Clinical, Cytologic, and Radiologic Correlation
title_short Hemorrhagic Meningitis Due to Varicella-Zoster Virus: A Case Report With Clinical, Cytologic, and Radiologic Correlation
title_sort hemorrhagic meningitis due to varicella-zoster virus: a case report with clinical, cytologic, and radiologic correlation
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720349/
https://www.ncbi.nlm.nih.gov/pubmed/36479400
http://dx.doi.org/10.7759/cureus.31113
work_keys_str_mv AT gorolayvineet hemorrhagicmeningitisduetovaricellazostervirusacasereportwithclinicalcytologicandradiologiccorrelation
AT martensdavid hemorrhagicmeningitisduetovaricellazostervirusacasereportwithclinicalcytologicandradiologiccorrelation
AT satgunaseelanlaveniya hemorrhagicmeningitisduetovaricellazostervirusacasereportwithclinicalcytologicandradiologiccorrelation
AT vancamplouise hemorrhagicmeningitisduetovaricellazostervirusacasereportwithclinicalcytologicandradiologiccorrelation
AT winklergemma hemorrhagicmeningitisduetovaricellazostervirusacasereportwithclinicalcytologicandradiologiccorrelation