Short-term oral pre-exposure prophylaxis against HIV-1 modulates the transcriptome of foreskin tissue in young men in Africa

Whilst short-term oral pre-exposure prophylaxis (PrEP) with antiretroviral drugs in men who have sex with men has shown protection against HIV-1 infection, the impact of this regimen on the in vivo foreskin transcriptome is unknown. We collected foreskin tissue after voluntary medical male circumcis...

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Detalles Bibliográficos
Autores principales: Petkov, Stefan, Herrera, Carolina, Else, Laura, Lebina, Limakatso, Opoka, Daniel, Seiphetlo, Thabiso B., Pillay, Azure-Dee AP., Mugaba, Susan, Namubiru, Patricia, Odoch, Geoffrey, Ssemata, Andrew S., Serwanga, Jennifer, Kaleebu, Pontiano, Webb, Emily L., Khoo, Saye, Martinson, Neil, Gray, Clive M., Fox, Julie, Chiodi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720390/
https://www.ncbi.nlm.nih.gov/pubmed/36479111
http://dx.doi.org/10.3389/fimmu.2022.1009978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720390/
https://www.ncbi.nlm.nih.gov/pubmed/36479111
http://dx.doi.org/10.3389/fimmu.2022.1009978

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