Tumor Mutational Burden by Whole-Genome Sequencing in Resected NSCLC of Never Smokers

BACKGROUND: Data are scarce about tumor mutational burden (TMB) as a biomarker in never smokers with non–small cell lung cancer (NSCLC). METHODS: TMB was assessed by whole-genome sequencing (WGS) and compared with in silico reduced whole-exome sequencing (WES) and targeted commercial next-generation...

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Detalles Bibliográficos
Autores principales: Ruel, Louis-Jacques, Li, Zhonglin, Gaudreault, Nathalie, Henry, Cyndi, Saavedra Armero, Victoria, Boudreau, Dominique K., Zhang, Tongwu, Landi, Maria Teresa, Labbé, Catherine, Couture, Christian, Desmeules, Patrice, Joubert, Philippe, Bossé, Yohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720425/
https://www.ncbi.nlm.nih.gov/pubmed/36126278
http://dx.doi.org/10.1158/1055-9965.EPI-22-0630

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