RNA-Based Classification of Homologous Recombination Deficiency in Racially Diverse Patients with Breast Cancer

BACKGROUND: Aberrant expression of DNA repair pathways such as homologous recombination (HR) can lead to DNA repair imbalance, genomic instability, and altered chemotherapy response. DNA repair imbalance may predict prognosis, but variation in DNA repair in diverse cohorts of breast cancer patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Walens, Andrea, Van Alsten, Sarah C., Olsson, Linnea T., Smith, Markia A., Lockhart, Alex, Gao, Xiaohua, Hamilton, Alina M., Kirk, Erin L., Love, Michael I., Gupta, Gaorav P., Perou, Charles M., Vaziri, Cyrus, Hoadley, Katherine A., Troester, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720427/
https://www.ncbi.nlm.nih.gov/pubmed/36129803
http://dx.doi.org/10.1158/1055-9965.EPI-22-0590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720427/
https://www.ncbi.nlm.nih.gov/pubmed/36129803
http://dx.doi.org/10.1158/1055-9965.EPI-22-0590

Ejemplares similares