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X-ray diffraction data for the C5a-peptidase mutant with modified activity and specificity

The Streptococcal C5a peptidase (ScpA) specifically inactivates the human complement factor hC5a, a potent anaphylatoxin recently identified as a therapeutic target for treatment of COVID-19 infections. Engineering of ScpA to enhance its potential as a therapeutic will require detailed examination o...

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Detalles Bibliográficos
Autores principales: Kagawa, Todd F., Jain, Monica, Cooney, Jakki C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720508/
https://www.ncbi.nlm.nih.gov/pubmed/36478677
http://dx.doi.org/10.1016/j.dib.2022.108778

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