Cargando…

Neuroinflammation-Related Proteins NOD2 and Spp1 Are Abnormally Upregulated in Amyotrophic Lateral Sclerosis

BACKGROUND AND OBJECTIVES: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of unknown etiology and poorly understood pathophysiology. There is no specific biomarker either for diagnosis or prognosis. The aim of our study was to investigate differentially expressed proteins in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Luna, Noemí, Carbayo, Álvaro, Dols-Icardo, Oriol, Turon-Sans, Janina, Reyes-Leiva, David, Illan-Gala, Ignacio, Jericó, Ivonne, Pagola-Lorz, Inma, Lleixà, Cinta, Querol, Luis, Rubio-Guerra, Sara, Alcolea, Daniel, Fortea, Juan, Lleó, Alberto, Cortés-Vicente, Elena, Rojas-Garcia, Ricardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720732/ https://www.ncbi.nlm.nih.gov/pubmed/36460480 http://dx.doi.org/10.1212/NXI.0000000000200072

Ejemplares similares

Pathophysiological Underpinnings of Extra-Motor Neurodegeneration in Amyotrophic Lateral Sclerosis: New Insights From Biomarker Studies
por: Reyes-Leiva, David, et al.
Publicado: (2022)

Motor cortex transcriptome reveals microglial key events in amyotrophic lateral sclerosis
por: Dols-Icardo, Oriol, et al.
Publicado: (2020)

Downregulation of miR-335-5P in Amyotrophic Lateral Sclerosis Can Contribute to Neuronal Mitochondrial Dysfunction and Apoptosis
por: De Luna, Noemi, et al.
Publicado: (2020)

Exploring the Disease-Associated Microglia State in Amyotrophic Lateral Sclerosis
por: Jauregui, Carlota, et al.
Publicado: (2023)

Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration
por: Cervantes González, Alba, et al.
Publicado: (2022)

Isotyping paranodal antibodies in inflammatory neuropathies: One step closer to precision care
por: Lleixà, Cinta, et al.
Publicado: (2020)

Novel Immunological and Therapeutic Insights in Guillain-Barré Syndrome and CIDP
por: Querol, Luis, et al.
Publicado: (2021)

Absence of pathogenic mutations in CD59 in chronic inflammatory demyelinating polyradiculoneuropathy
por: Duchateau, Lena, et al.
Publicado: (2019)

Correction: Absence of pathogenic mutations in CD59 in chronic inflammatory demyelinating polyradiculoneuropathy
por: Duchateau, Lena, et al.
Publicado: (2019)

Epidemiological study and genetic characterization of inherited muscle diseases in a northern Spanish region
por: Pagola-Lorz, Inmaculada, et al.
Publicado: (2019)

The Sant Pau Initiative on Neurodegeneration (SPIN) cohort: A data set for biomarker discovery and validation in neurodegenerative disorders
por: Alcolea, Daniel, et al.
Publicado: (2019)

Cortical microstructure in primary progressive aphasia: a multicenter study
por: Illán-Gala, Ignacio, et al.
Publicado: (2022)

Correction: Cortical microstructure in primary progressive aphasia: a multicenter study
por: Illán-Gala, Ignacio, et al.
Publicado: (2023)

Different pattern of CSF glial markers between dementia with Lewy bodies and Alzheimer’s disease
por: Morenas-Rodríguez, Estrella, et al.
Publicado: (2019)

Challenges associated with biomarker-based classification systems for Alzheimer's disease
por: Illán-Gala, Ignacio, et al.
Publicado: (2018)

A Novel Missense Variant Associated with A Splicing Defect in A Myopathic Form of PGK1 Deficiency in The Spanish Population
por: Garcia-Solaesa, Virginia, et al.
Publicado: (2019)

Differential levels of Neurofilament Light protein in cerebrospinal fluid in patients with a wide range of neurodegenerative disorders
por: Delaby, C., et al.
Publicado: (2020)

Liquid biopsy: a new source of candidate biomarkers in amyotrophic lateral sclerosis
por: Mendioroz, Maite, et al.
Publicado: (2018)

Immune Response and Safety of SARS-CoV-2 mRNA-1273 Vaccine in Patients With Myasthenia Gravis
por: Reyes-Leiva, David, et al.
Publicado: (2022)

Decreased CX3CL1 Levels in the Cerebrospinal Fluid of Patients With Alzheimer’s Disease
por: Perea, Juan R., et al.
Publicado: (2018)

Weight loss in the healthy elderly might be a non-cognitive sign of preclinical Alzheimer's disease
por: Jimenez, Amanda, et al.
Publicado: (2017)

Effect of monovalency on anti-contactin-1 IgG4
por: Taieb, Guillaume, et al.
Publicado: (2023)

Diagnostic Utility of Measuring Cerebral Atrophy in the Behavioral Variant of Frontotemporal Dementia and Association With Clinical Deterioration
por: Illán-Gala, Ignacio, et al.
Publicado: (2021)

IgG4 Valency Modulates the Pathogenicity of Anti–Neurofascin-155 IgG4 in Autoimmune Nodopathy
por: Jentzer, Alexandre, et al.
Publicado: (2022)

Reduced Number of Thymoma CTLA4-Positive Cells Is Associated With a Higher Probability of Developing Myasthenia Gravis
por: Álvarez-Velasco, Rodrigo, et al.
Publicado: (2023)

Cognitive decline in amyotrophic lateral sclerosis: Neuropathological substrate and genetic determinants
por: Borrego‐Écija, Sergi, et al.
Publicado: (2021)

The cognitive aftermath of COVID-19
por: Lleó, Alberto, et al.
Publicado: (2020)

APP‐derived peptides reflect neurodegeneration in frontotemporal dementia
por: Illán‐Gala, Ignacio, et al.
Publicado: (2019)

Evaluation of cerebrospinal fluid levels of synaptic vesicle protein, VAMP-2, across the sporadic Alzheimer’s disease continuum
por: Goossens, Julie, et al.
Publicado: (2023)

Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia
por: Zhu, Nuole, et al.
Publicado: (2021)

Correction: Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia
por: Zhu, Nuole, et al.
Publicado: (2023)

Novel PLEKHG5 mutations in a patient with childhood‐onset lower motor neuron disease
por: Gonzalez‐Quereda, Lidia, et al.
Publicado: (2020)

Neuroanatomical Quantitative Proteomics Reveals Common Pathogenic Biological Routes between Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)
por: Iridoy, Marina Oaia, et al.
Publicado: (2018)

Chronic inflammatory demyelinating polyneuropathy associated with contactin-1 antibodies in a child
por: Carrera-García, Laura, et al.
Publicado: (2019)

The Aβ1–42/Aβ1–40 ratio in CSF is more strongly associated to tau markers and clinical progression than Aβ1–42 alone
por: Delaby, Constance, et al.
Publicado: (2022)

YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer’s disease and other tauopathies
por: Querol-Vilaseca, Marta, et al.
Publicado: (2017)

AMYQ: An index to standardize quantitative amyloid load across PET tracers
por: Pegueroles, Jordi, et al.
Publicado: (2021)

Blood amyloid and tau biomarkers as predictors of cerebrospinal fluid profiles
por: Delaby, Constance, et al.
Publicado: (2022)

NOD1 and NOD2 Signaling in Infection and Inflammation
por: Moreira, Lilian O., et al.
Publicado: (2012)

A nod to the bond between NOD2 and mycobacteria
por: Dubé, Jean-Yves, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_67h9ag2qluag5tho7gjg2k8f4o