Cargando…

Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis

OBJECTIVE: To identify whether median nerve stimulation (MNS) may be a potential candidate for the treatment of consciousness disorders via a systematic review and meta-analysis. METHODS: PubMed, Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and SinoMed...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Peng, Cao, Wei, Zhou, Hong, Zhang, Huan Xin, Zhang, Lunzhong, Liu, Li, Sui, Yunlong, Zhang, Zhen, Yin, Xiaoyu, Yang, Fan, Kong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720824/
https://www.ncbi.nlm.nih.gov/pubmed/36448965
http://dx.doi.org/10.1177/03000605221134467
_version_ 1784843637093302272
author Wang, Peng
Cao, Wei
Zhou, Hong
Zhang, Huan Xin
Zhang, Lunzhong
Liu, Li
Sui, Yunlong
Zhang, Zhen
Yin, Xiaoyu
Yang, Fan
Kong, Li
author_facet Wang, Peng
Cao, Wei
Zhou, Hong
Zhang, Huan Xin
Zhang, Lunzhong
Liu, Li
Sui, Yunlong
Zhang, Zhen
Yin, Xiaoyu
Yang, Fan
Kong, Li
author_sort Wang, Peng
collection PubMed
description OBJECTIVE: To identify whether median nerve stimulation (MNS) may be a potential candidate for the treatment of consciousness disorders via a systematic review and meta-analysis. METHODS: PubMed, Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and SinoMed databases were searched. Risk of bias was assessed using the Cochrane Collaboration’s tool. The Glasgow Coma Scale (GCS), Disability Rating Scale (DRS), electroencephalogram (EEG), days in the Intensive Care Unit (ICU), and cerebral blood flow measures were compared between the median nerve stimulation and control groups. The meta-analysis was conducted using Review Manager software. RESULTS: We identified 2244 studies, of which 23 (with data from 1856 patients) qualified for the analysis. MNS improved GCS scores (mean difference [MD] = 2.15), EEG scores (MD = 1.61), cerebral mean blood flow velocity (MD = 4.23), and cerebral systolic blood flow velocity (MD = 10.51). Furthermore, it decreased DRS scores (MD = −1.77) and days in the ICU (MD = −2.02). The effects of MNS on GCS scores increased with longer treatments (1 week, MD = 1.03; 1 month, MD = 2.35) and were better with right MNS (right, MD = 2.36; bilateral, MD = 1.72). CONCLUSIONS: MNS may promote recovery from consciousness disorders.
format Online
Article
Text
id pubmed-9720824
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-97208242022-12-06 Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis Wang, Peng Cao, Wei Zhou, Hong Zhang, Huan Xin Zhang, Lunzhong Liu, Li Sui, Yunlong Zhang, Zhen Yin, Xiaoyu Yang, Fan Kong, Li J Int Med Res Meta Analysis OBJECTIVE: To identify whether median nerve stimulation (MNS) may be a potential candidate for the treatment of consciousness disorders via a systematic review and meta-analysis. METHODS: PubMed, Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and SinoMed databases were searched. Risk of bias was assessed using the Cochrane Collaboration’s tool. The Glasgow Coma Scale (GCS), Disability Rating Scale (DRS), electroencephalogram (EEG), days in the Intensive Care Unit (ICU), and cerebral blood flow measures were compared between the median nerve stimulation and control groups. The meta-analysis was conducted using Review Manager software. RESULTS: We identified 2244 studies, of which 23 (with data from 1856 patients) qualified for the analysis. MNS improved GCS scores (mean difference [MD] = 2.15), EEG scores (MD = 1.61), cerebral mean blood flow velocity (MD = 4.23), and cerebral systolic blood flow velocity (MD = 10.51). Furthermore, it decreased DRS scores (MD = −1.77) and days in the ICU (MD = −2.02). The effects of MNS on GCS scores increased with longer treatments (1 week, MD = 1.03; 1 month, MD = 2.35) and were better with right MNS (right, MD = 2.36; bilateral, MD = 1.72). CONCLUSIONS: MNS may promote recovery from consciousness disorders. SAGE Publications 2022-11-30 /pmc/articles/PMC9720824/ /pubmed/36448965 http://dx.doi.org/10.1177/03000605221134467 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Meta Analysis
Wang, Peng
Cao, Wei
Zhou, Hong
Zhang, Huan Xin
Zhang, Lunzhong
Liu, Li
Sui, Yunlong
Zhang, Zhen
Yin, Xiaoyu
Yang, Fan
Kong, Li
Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis
title Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis
title_full Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis
title_fullStr Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis
title_full_unstemmed Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis
title_short Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis
title_sort efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis
topic Meta Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720824/
https://www.ncbi.nlm.nih.gov/pubmed/36448965
http://dx.doi.org/10.1177/03000605221134467
work_keys_str_mv AT wangpeng efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT caowei efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT zhouhong efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT zhanghuanxin efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT zhanglunzhong efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT liuli efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT suiyunlong efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT zhangzhen efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT yinxiaoyu efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT yangfan efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis
AT kongli efficacyofmediannerveelectricalstimulationontherecoveryofpatientswithconsciousnessdisordersasystematicreviewandmetaanalysis