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Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis
OBJECTIVE: To identify whether median nerve stimulation (MNS) may be a potential candidate for the treatment of consciousness disorders via a systematic review and meta-analysis. METHODS: PubMed, Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and SinoMed...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720824/ https://www.ncbi.nlm.nih.gov/pubmed/36448965 http://dx.doi.org/10.1177/03000605221134467 |
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author | Wang, Peng Cao, Wei Zhou, Hong Zhang, Huan Xin Zhang, Lunzhong Liu, Li Sui, Yunlong Zhang, Zhen Yin, Xiaoyu Yang, Fan Kong, Li |
author_facet | Wang, Peng Cao, Wei Zhou, Hong Zhang, Huan Xin Zhang, Lunzhong Liu, Li Sui, Yunlong Zhang, Zhen Yin, Xiaoyu Yang, Fan Kong, Li |
author_sort | Wang, Peng |
collection | PubMed |
description | OBJECTIVE: To identify whether median nerve stimulation (MNS) may be a potential candidate for the treatment of consciousness disorders via a systematic review and meta-analysis. METHODS: PubMed, Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and SinoMed databases were searched. Risk of bias was assessed using the Cochrane Collaboration’s tool. The Glasgow Coma Scale (GCS), Disability Rating Scale (DRS), electroencephalogram (EEG), days in the Intensive Care Unit (ICU), and cerebral blood flow measures were compared between the median nerve stimulation and control groups. The meta-analysis was conducted using Review Manager software. RESULTS: We identified 2244 studies, of which 23 (with data from 1856 patients) qualified for the analysis. MNS improved GCS scores (mean difference [MD] = 2.15), EEG scores (MD = 1.61), cerebral mean blood flow velocity (MD = 4.23), and cerebral systolic blood flow velocity (MD = 10.51). Furthermore, it decreased DRS scores (MD = −1.77) and days in the ICU (MD = −2.02). The effects of MNS on GCS scores increased with longer treatments (1 week, MD = 1.03; 1 month, MD = 2.35) and were better with right MNS (right, MD = 2.36; bilateral, MD = 1.72). CONCLUSIONS: MNS may promote recovery from consciousness disorders. |
format | Online Article Text |
id | pubmed-9720824 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-97208242022-12-06 Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis Wang, Peng Cao, Wei Zhou, Hong Zhang, Huan Xin Zhang, Lunzhong Liu, Li Sui, Yunlong Zhang, Zhen Yin, Xiaoyu Yang, Fan Kong, Li J Int Med Res Meta Analysis OBJECTIVE: To identify whether median nerve stimulation (MNS) may be a potential candidate for the treatment of consciousness disorders via a systematic review and meta-analysis. METHODS: PubMed, Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and SinoMed databases were searched. Risk of bias was assessed using the Cochrane Collaboration’s tool. The Glasgow Coma Scale (GCS), Disability Rating Scale (DRS), electroencephalogram (EEG), days in the Intensive Care Unit (ICU), and cerebral blood flow measures were compared between the median nerve stimulation and control groups. The meta-analysis was conducted using Review Manager software. RESULTS: We identified 2244 studies, of which 23 (with data from 1856 patients) qualified for the analysis. MNS improved GCS scores (mean difference [MD] = 2.15), EEG scores (MD = 1.61), cerebral mean blood flow velocity (MD = 4.23), and cerebral systolic blood flow velocity (MD = 10.51). Furthermore, it decreased DRS scores (MD = −1.77) and days in the ICU (MD = −2.02). The effects of MNS on GCS scores increased with longer treatments (1 week, MD = 1.03; 1 month, MD = 2.35) and were better with right MNS (right, MD = 2.36; bilateral, MD = 1.72). CONCLUSIONS: MNS may promote recovery from consciousness disorders. SAGE Publications 2022-11-30 /pmc/articles/PMC9720824/ /pubmed/36448965 http://dx.doi.org/10.1177/03000605221134467 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Meta Analysis Wang, Peng Cao, Wei Zhou, Hong Zhang, Huan Xin Zhang, Lunzhong Liu, Li Sui, Yunlong Zhang, Zhen Yin, Xiaoyu Yang, Fan Kong, Li Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis |
title | Efficacy of median nerve electrical stimulation on the recovery of
patients with consciousness disorders: a systematic review and
meta-analysis |
title_full | Efficacy of median nerve electrical stimulation on the recovery of
patients with consciousness disorders: a systematic review and
meta-analysis |
title_fullStr | Efficacy of median nerve electrical stimulation on the recovery of
patients with consciousness disorders: a systematic review and
meta-analysis |
title_full_unstemmed | Efficacy of median nerve electrical stimulation on the recovery of
patients with consciousness disorders: a systematic review and
meta-analysis |
title_short | Efficacy of median nerve electrical stimulation on the recovery of
patients with consciousness disorders: a systematic review and
meta-analysis |
title_sort | efficacy of median nerve electrical stimulation on the recovery of
patients with consciousness disorders: a systematic review and
meta-analysis |
topic | Meta Analysis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720824/ https://www.ncbi.nlm.nih.gov/pubmed/36448965 http://dx.doi.org/10.1177/03000605221134467 |
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