A review of the therapeutic management of ulcerative colitis

Ulcerative colitis (UC) is a chronic relapsing and remitting gastrointestinal disorder of uncertain aetiology. The last two decades have seen an expansion in the therapeutic arsenal used to treat UC. This has resulted in improved clinical remission and response rates. Nonetheless, staples in our cur...

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Detalles Bibliográficos
Autores principales: Aslam, Nasar, Lo, Sheng Wei, Sikafi, Rafid, Barnes, Tom, Segal, Jonathan, Smith, Philip J, Limdi, Jimmy K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720837/
https://www.ncbi.nlm.nih.gov/pubmed/36478780
http://dx.doi.org/10.1177/17562848221138160
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author Aslam, Nasar
Lo, Sheng Wei
Sikafi, Rafid
Barnes, Tom
Segal, Jonathan
Smith, Philip J
Limdi, Jimmy K
author_facet Aslam, Nasar
Lo, Sheng Wei
Sikafi, Rafid
Barnes, Tom
Segal, Jonathan
Smith, Philip J
Limdi, Jimmy K
author_sort Aslam, Nasar
collection PubMed
description Ulcerative colitis (UC) is a chronic relapsing and remitting gastrointestinal disorder of uncertain aetiology. The last two decades have seen an expansion in the therapeutic arsenal used to treat UC. This has resulted in improved clinical remission and response rates. Nonetheless, staples in our current medical management originate from trials conducted in the early 20th century. In this review article, we aim to outline the key milestones in the history of the medical management of UC in addition to highlighting promising therapeutic developments for the future.
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spelling pubmed-97208372022-12-06 A review of the therapeutic management of ulcerative colitis Aslam, Nasar Lo, Sheng Wei Sikafi, Rafid Barnes, Tom Segal, Jonathan Smith, Philip J Limdi, Jimmy K Therap Adv Gastroenterol Review Ulcerative colitis (UC) is a chronic relapsing and remitting gastrointestinal disorder of uncertain aetiology. The last two decades have seen an expansion in the therapeutic arsenal used to treat UC. This has resulted in improved clinical remission and response rates. Nonetheless, staples in our current medical management originate from trials conducted in the early 20th century. In this review article, we aim to outline the key milestones in the history of the medical management of UC in addition to highlighting promising therapeutic developments for the future. SAGE Publications 2022-11-29 /pmc/articles/PMC9720837/ /pubmed/36478780 http://dx.doi.org/10.1177/17562848221138160 Text en © The Author(s), 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Aslam, Nasar
Lo, Sheng Wei
Sikafi, Rafid
Barnes, Tom
Segal, Jonathan
Smith, Philip J
Limdi, Jimmy K
A review of the therapeutic management of ulcerative colitis
title A review of the therapeutic management of ulcerative colitis
title_full A review of the therapeutic management of ulcerative colitis
title_fullStr A review of the therapeutic management of ulcerative colitis
title_full_unstemmed A review of the therapeutic management of ulcerative colitis
title_short A review of the therapeutic management of ulcerative colitis
title_sort review of the therapeutic management of ulcerative colitis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720837/
https://www.ncbi.nlm.nih.gov/pubmed/36478780
http://dx.doi.org/10.1177/17562848221138160
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