A case report involving suppressed nuclear receptor transcription factors 4a1 and Stevens-Johnson syndrome induced by a single dose of pembrolizumab and successfully treated with early steroid administration, resulting in complete remission of stage III lung cancer

BACKGROUND: Immunotherapy with immune checkpoint inhibitors is associated with immune-related adverse events (irAEs). A positive correlation between treatment efficacy and irAEs has been reported. Clinical indicators are required for appropriate interventions, such as steroid administration, to prev...

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Detalles Bibliográficos
Autores principales: Machida, Maiko, Yamazaki, Chika, Kouda, Nao, Hanai, Yousei, Sato, Hideki, Konda, Ainari, Yamagata, Yuka, Itho, Tatsuya, Aisaka, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720965/
https://www.ncbi.nlm.nih.gov/pubmed/36464708
http://dx.doi.org/10.1186/s40780-022-00261-y

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