Ketogenic diet as a glycine lowering therapy in nonketotic hyperglycinemia and impact on brain glycine levels

BACKGROUND: Nonketotic hyperglycinemia (NKH) is a severe neurometabolic disorder characterized by increased glycine levels. Current glycine reduction therapy uses high doses of sodium benzoate. The ketogenic diet (KD) may represent an alternative method of glycine reduction. AIM: We aimed to assess...

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Detalles Bibliográficos
Autores principales: Shelkowitz, Emily, Saneto, Russell P., Al-Hertani, Walla, Lubout, Charlotte M. A., Stence, Nicholas V., Brown, Mark S., Long, Patrick, Walleigh, Diana, Nelson, Julie A., Perez, Francisco E., Shaw, Dennis W. W., Michl, Emma J., Van Hove, Johan L. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720968/
https://www.ncbi.nlm.nih.gov/pubmed/36471344
http://dx.doi.org/10.1186/s13023-022-02581-6

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