Cargando…

Proteomic profiling of circulating plasma exosomes reveals novel biomarkers of Alzheimer’s disease

BACKGROUND: Neuronal- and astrocyte-derived exosomes have been identified as an optimal source for screening biomarkers for Alzheimer’s disease (AD). However, few studies focus on the bulk exosome population isolated from plasma of AD. This study investigated whether proteins in bulk exosomes can ai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Huimin, Pang, Yana, Wang, Qi, Qin, Wei, Wei, Cuibai, Li, Ying, Li, Tingting, Li, Fangyu, Wang, Qigeng, Li, Yan, Wei, Yiping, Jia, Longfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720984/ https://www.ncbi.nlm.nih.gov/pubmed/36471423 http://dx.doi.org/10.1186/s13195-022-01133-1

Ejemplares similares

Blood neuro‐exosomal synaptic proteins predict Alzheimer's disease at the asymptomatic stage
por: Jia, Longfei, et al.
Publicado: (2020)

Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease
por: Jia, Longfei, et al.
Publicado: (2021)

A metabolite panel that differentiates Alzheimer's disease from other dementia types
por: Jia, Longfei, et al.
Publicado: (2021)

Detection of plasma Aβ seeding activity by a newly developed analyzer for diagnosis of Alzheimer’s disease
por: Jia, Jianping, et al.
Publicado: (2022)

Plasma biomarkers predict Alzheimer’s disease before clinical onset in Chinese cohorts
por: Cai, Huimin, et al.
Publicado: (2023)

Monetary costs of Alzheimer’s disease in China: protocol for a cluster-randomised observational study
por: Li, Fangyu, et al.
Publicado: (2017)

A blood-based composite panel that screens Alzheimer’s disease
por: Wang, Yan, et al.
Publicado: (2023)

Association of accelerated long-term forgetting and senescence-related blood-borne factors in asymptomatic individuals from families with autosomal dominant Alzheimer’s disease
por: Yang, Jianwei, et al.
Publicado: (2021)

Phosphorylated Tau 181 Serum Levels Predict Alzheimer’s Disease in the Preclinical Stage
por: Qin, Wei, et al.
Publicado: (2022)

Aberrant palmitoylation caused by a ZDHHC21 mutation contributes to pathophysiology of Alzheimer’s disease
por: Li, Wenwen, et al.
Publicado: (2023)

A circular RNA blood panel that differentiates Alzheimer’s disease from other dementia types
por: Ren, Ziye, et al.
Publicado: (2022)

Evaluation of plasma exosomal microRNAs as circulating biomarkers for progression and metastasis of gastric cancer
por: Chen, Yuqi, et al.
Publicado: (2020)

Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer’s disease
por: Qin, Wei, et al.
Publicado: (2021)

Effects of gene mutation and disease progression on representative neural circuits in familial Alzheimer’s disease
por: Quan, Meina, et al.
Publicado: (2020)

Proteomics Analysis of Exosomes From Patients With Active Tuberculosis Reveals Infection Profiles and Potential Biomarkers
por: Zhang, Min, et al.
Publicado: (2022)

Plasma Exosomal Proteomic Pattern of Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis
por: Xie, Yan, et al.
Publicado: (2022)

Tumor-originated exosomal lncUEGC1 as a circulating biomarker for early-stage gastric cancer
por: Lin, Ling-Yun, et al.
Publicado: (2018)

Circulating exosomal microRNAs as novel potential detection biomarkers in pancreatic cancer
por: Wu, Lun, et al.
Publicado: (2020)

Serum Exosomal MicroRNAs as Potential Circulating Biomarkers for Endometriosis
por: Zhang, Lu, et al.
Publicado: (2020)

Corrigendum: Plasma Exosomal Proteomic Pattern of Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis
por: Xie, Yan, et al.
Publicado: (2022)

Circulating plasma exosomal miRNA profiles serve as potential metastasis-related biomarkers for hepatocellular carcinoma
por: Huang, Chunyu, et al.
Publicado: (2021)

Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging
por: Abner, Erin L., et al.
Publicado: (2016)

Functional Properties of Circulating Exosomes Mediated by Surface-Attached Plasma Proteins
por: Shtam, Tatiana, et al.
Publicado: (2018)

Proteomics Analysis of Plasma-Derived Exosomes Unveils the Aberrant Complement and Coagulation Cascades in Dermatomyositis/Polymyositis
por: Meng, Shuhui, et al.
Publicado: (2022)

Differential proteomic analysis of plasma-derived exosomes as diagnostic biomarkers for chronic HBV-related liver disease
por: Ye, Bo, et al.
Publicado: (2022)

Plasma exosome proteomics reveals the pathogenesis mechanism of post-stroke cognitive impairment
por: Qi, Baoyun, et al.
Publicado: (2023)

Circulating Exosomal miRNAs as Novel Biomarkers for Stable Coronary Artery Disease
por: Zhang, Ping, et al.
Publicado: (2020)

Shared and unique effects of ApoEε4 and pathogenic gene mutation on cognition and imaging in preclinical familial Alzheimer’s disease
por: Quan, Meina, et al.
Publicado: (2023)

The APOE ε4 exerts differential effects on familial and other subtypes of Alzheimer's disease
por: Jia, Longfei, et al.
Publicado: (2020)

Screening of plasma exosomal lncRNAs to identify potential biomarkers for obstructive sleep apnea
por: Chen, Xunxun, et al.
Publicado: (2022)

Proteomics of serum exosomes identified fibulin-1 as a novel biomarker for mild cognitive impairment
por: Chen, Bo, et al.
Publicado: (2022)

Quantitative Proteomic Analysis of Plasma Exosomes to Identify the Candidate Biomarker of Imatinib Resistance in Chronic Myeloid Leukemia Patients
por: Li, Mei-Yong, et al.
Publicado: (2021)

Identification of KIAA0513 and Other Hub Genes Associated With Alzheimer Disease Using Weighted Gene Coexpression Network Analysis
por: Zhu, Min, et al.
Publicado: (2020)

Identification of thrombotic biomarkers in orthopedic surgery patients by plasma proteomics
por: Liu, Cui-Qing, et al.
Publicado: (2023)

Circulating plasma and exosome levels of the miR-320 family as a non-invasive biomarker for methamphetamine use disorder
por: Xu, Wenjin, et al.
Publicado: (2023)

Exosome Composition and Seminal Plasma Proteome: A Promising Source of Biomarkers of Male Infertility
por: Candenas, Luz, et al.
Publicado: (2020)

Comparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis
por: Li, Sini, et al.
Publicado: (2023)

Identification of Three Circulating MicroRNAs in Plasma as Clinical Biomarkers for Breast Cancer Detection
por: Wang, Shuang, et al.
Publicado: (2022)

Clinical and biological significance of circulating tumor cells, circulating tumor DNA, and exosomes as biomarkers in colorectal cancer
por: Jia, Shiyu, et al.
Publicado: (2017)

Circulating Exosomal microRNAs as Biomarkers of Systemic Lupus Erythematosus
por: Li, Wengen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g722p9rultfdgrtpghfg66co4b