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Targeting treatment of bladder cancer using PTK7 aptamer-gemcitabine conjugate

BACKGROUND: Gemcitabine (GEM) is one of the first-line chemotherapies for bladder cancer (BC), but the GEMs cannot recognize cancer cells and have a low long-term response rate and high recurrence rate with side effects during the treatment of BC. Targeted transport of GEMs to mediate cytotoxicity t...

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Detalles Bibliográficos
Autores principales:	Xiang, Wei, Peng, Yongbo, Zeng, Hongliang, Yu, Chunping, Zhang, Qun, Liu, Biao, Liu, Jiahao, Hu, Xing, Wei, Wensu, Deng, Minhua, Wang, Ning, Liu, Xuewen, Xie, Jianfei, Hou, Weibin, Tang, Jin, Long, Zhi, Wang, Long, Liu, Jianye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721011/ https://www.ncbi.nlm.nih.gov/pubmed/36471380 http://dx.doi.org/10.1186/s40824-022-00328-9

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