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Optimization of the preoperative requirements of blood units for the surgical treatment of extra-abdominal soft tissue sarcoma: the TRANSAR score

BACKGROUND AND OBJECTIVES: Excessive preoperative blood orders frequently occur during the preoperative planning of resections of sarcomas. We aimed to develop a prediction score model that would be able to identify a patient cohort in which the cross-matching could be safely evaded. PATIENTS AND ME...

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Autores principales: Farzaliyev, Farhad, Steinau, Hans-Ulrich, Halmyradov, Atajan, Malamutmann, Eugen, Sleutel, Arie, Illg, Claudius, Podleska, Lars Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721031/
https://www.ncbi.nlm.nih.gov/pubmed/36464677
http://dx.doi.org/10.1186/s12957-022-02839-0
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author Farzaliyev, Farhad
Steinau, Hans-Ulrich
Halmyradov, Atajan
Malamutmann, Eugen
Sleutel, Arie
Illg, Claudius
Podleska, Lars Erik
author_facet Farzaliyev, Farhad
Steinau, Hans-Ulrich
Halmyradov, Atajan
Malamutmann, Eugen
Sleutel, Arie
Illg, Claudius
Podleska, Lars Erik
author_sort Farzaliyev, Farhad
collection PubMed
description BACKGROUND AND OBJECTIVES: Excessive preoperative blood orders frequently occur during the preoperative planning of resections of sarcomas. We aimed to develop a prediction score model that would be able to identify a patient cohort in which the cross-matching could be safely evaded. PATIENTS AND METHODS: We retrospectively analyzed data of 309 consecutive patients with extra-abdominal soft tissue sarcomas treated between September 2012 and December 2014. Scorecard scores for variables were calculated and summarized to a total score that can be used for risk stratification. The score was used in a logistic regression model. Results of the optimized model were described as a receiver operating characteristic curve. RESULTS: Preoperative units of red blood cells were requested for 206 (66.7%) patients, of which only 31 (10%) received them. Five parameters were identified with high predictive power. In the visualized barplot, there was an increased risk of blood transfusion with a higher score of TRANSAR. CONCLUSION: A TRANSAR score is a new tool that can predict the probability of transfusion for patients with sarcoma. This may reduce the number of preoperative cross-matching and blood product ordering and associated costs without compromising patient care. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12957-022-02839-0.
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spelling pubmed-97210312022-12-06 Optimization of the preoperative requirements of blood units for the surgical treatment of extra-abdominal soft tissue sarcoma: the TRANSAR score Farzaliyev, Farhad Steinau, Hans-Ulrich Halmyradov, Atajan Malamutmann, Eugen Sleutel, Arie Illg, Claudius Podleska, Lars Erik World J Surg Oncol Research BACKGROUND AND OBJECTIVES: Excessive preoperative blood orders frequently occur during the preoperative planning of resections of sarcomas. We aimed to develop a prediction score model that would be able to identify a patient cohort in which the cross-matching could be safely evaded. PATIENTS AND METHODS: We retrospectively analyzed data of 309 consecutive patients with extra-abdominal soft tissue sarcomas treated between September 2012 and December 2014. Scorecard scores for variables were calculated and summarized to a total score that can be used for risk stratification. The score was used in a logistic regression model. Results of the optimized model were described as a receiver operating characteristic curve. RESULTS: Preoperative units of red blood cells were requested for 206 (66.7%) patients, of which only 31 (10%) received them. Five parameters were identified with high predictive power. In the visualized barplot, there was an increased risk of blood transfusion with a higher score of TRANSAR. CONCLUSION: A TRANSAR score is a new tool that can predict the probability of transfusion for patients with sarcoma. This may reduce the number of preoperative cross-matching and blood product ordering and associated costs without compromising patient care. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12957-022-02839-0. BioMed Central 2022-12-04 /pmc/articles/PMC9721031/ /pubmed/36464677 http://dx.doi.org/10.1186/s12957-022-02839-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Farzaliyev, Farhad
Steinau, Hans-Ulrich
Halmyradov, Atajan
Malamutmann, Eugen
Sleutel, Arie
Illg, Claudius
Podleska, Lars Erik
Optimization of the preoperative requirements of blood units for the surgical treatment of extra-abdominal soft tissue sarcoma: the TRANSAR score
title Optimization of the preoperative requirements of blood units for the surgical treatment of extra-abdominal soft tissue sarcoma: the TRANSAR score
title_full Optimization of the preoperative requirements of blood units for the surgical treatment of extra-abdominal soft tissue sarcoma: the TRANSAR score
title_fullStr Optimization of the preoperative requirements of blood units for the surgical treatment of extra-abdominal soft tissue sarcoma: the TRANSAR score
title_full_unstemmed Optimization of the preoperative requirements of blood units for the surgical treatment of extra-abdominal soft tissue sarcoma: the TRANSAR score
title_short Optimization of the preoperative requirements of blood units for the surgical treatment of extra-abdominal soft tissue sarcoma: the TRANSAR score
title_sort optimization of the preoperative requirements of blood units for the surgical treatment of extra-abdominal soft tissue sarcoma: the transar score
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721031/
https://www.ncbi.nlm.nih.gov/pubmed/36464677
http://dx.doi.org/10.1186/s12957-022-02839-0
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