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Multifunctional ROS-Responsive and TME-Modulated Lipid-Polymer Hybrid Nanoparticles for Enhanced Tumor Penetration

PURPOSE: To enhance tumor penetration by formulation design and tumor microenvironment (TME) modulation, herein a novel reactive oxygen species (ROS)-responsive size/shape transformable lipid-polymer hybrid nanoparticle (LPN) has been fabricated for the co-delivery of an anticancer and collagen-inhi...

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Detalles Bibliográficos
Autores principales:	Ni, Rui, Huang, Lele, Li, Zhen, Zhang, Wenli, Wang, Yajie, Shen, Yan, Wang, Jianxin, Lu, Weigen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721131/ https://www.ncbi.nlm.nih.gov/pubmed/36478745 http://dx.doi.org/10.2147/IJN.S383517

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