Structural patterns of SARS-CoV-2 variants of concern (alpha, beta, gamma, delta) spike protein are influenced by variant-specific amino acid mutations: A computational study with implications on viral evolution

SARS-CoV-2 (SARS2) regularly mutates resulting to variants of concern (VOC) which have higher virulence and transmissibility rates while concurrently evading available therapeutic strategies. This highlights the importance of amino acid mutations occurring in the SARS2 spike protein structure since...

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Detalles Bibliográficos
Autores principales: Cueno, Marni E., Wada, Kanta, Tsuji, Arisa, Ishikawa, Kouta, Imai, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721161/
https://www.ncbi.nlm.nih.gov/pubmed/36473508
http://dx.doi.org/10.1016/j.jtbi.2022.111376

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