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Real-World Experience with a 60-mm-Long Stent in the Setting of Primary Percutaneous Coronary Intervention

INTRODUCTION: Primary percutaneous coronary intervention (PPCI) represents a timely procedure that requires speedy revascularization. Moreover, PPCI in diffuse coronary lesions remains to be challenging even in the hands of experienced operators as the use of a long stent may increase the difficulty...

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Autores principales: Thevan, Babu, Abdulrahman, Abdulkarim, Subbramaniyam, Suddharsan, Chachar, Tarique Shahzad, Yousif, Nooraldaem, Noor, Husam A., Amin, Haitham, Abdulqader, Fuad, Shivappa, Sadananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721184/
https://www.ncbi.nlm.nih.gov/pubmed/36479168
http://dx.doi.org/10.4103/heartviews.heartviews_2_22
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author Thevan, Babu
Abdulrahman, Abdulkarim
Subbramaniyam, Suddharsan
Chachar, Tarique Shahzad
Yousif, Nooraldaem
Noor, Husam A.
Amin, Haitham
Abdulqader, Fuad
Shivappa, Sadananda
author_facet Thevan, Babu
Abdulrahman, Abdulkarim
Subbramaniyam, Suddharsan
Chachar, Tarique Shahzad
Yousif, Nooraldaem
Noor, Husam A.
Amin, Haitham
Abdulqader, Fuad
Shivappa, Sadananda
author_sort Thevan, Babu
collection PubMed
description INTRODUCTION: Primary percutaneous coronary intervention (PPCI) represents a timely procedure that requires speedy revascularization. Moreover, PPCI in diffuse coronary lesions remains to be challenging even in the hands of experienced operators as the use of a long stent may increase the difficulty of the procedure in terms of stent delivery, deployment, and optimization. However, the practicability and clinical outcomes of deployment of a 60-mm-long stent in the setting of PPCI remain to be determined. METHODS: The study is a retrospective observational analysis in a prospective cohort. The prospectively gathered data of consecutive patients from June 2016 to December 2019, who underwent PPCI with BioMime sirolimus-eluting stents 2.5–3.0/60 mm or 3.0–3.5/60 mm were analyzed at 1 year regarding the primary outcome of major adverse cardiovascular and cerebrovascular events (MACCE) and target lesion revascularization (TLR). RESULTS: A total of 88 cases were included in the study; 23 cases underwent PPCI, whereas 65 underwent nonPPCI. The PPCI group had a mean age of 65.7 ± 10.9 years compared with 63.3 ± 9.6 years (P = 0.34) in the nonPPCI group. Eighty-three percentage of PPCI were males compared with 94% of their nonPPCI counterparts (P = 0.20). In addition, the prevalence of hypertension was more common in the PPCI group (87% vs. 63%, P = 0.03). There was no statistically significant difference between the two groups regarding other comorbidities. The most common culprit vessel was the left anterior descending artery (57%) in the PPCI group and the right coronary artery (58%) in the nonPPCI. The use of a stent with a diameter of 2.5–3.0 mm was more common in both groups (61% in PPCI vs. 66% in nonPPCI, P = 0.8). MACCE occurred in four patients during a year of follow-up. One occurred in the PPCI group (4%) compared with three in the nonPPCI group (5%) (P = 1.00). TLR was required in two cases, one in each group (4% vs. 2%, P = 0.46). CONCLUSION: The use of a 60-mm-long stent in the setting of PPCI has an excellent 12-month outcome in procedural success, MACCE, and TLR. Large randomized studies are required to confirm these results.
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spelling pubmed-97211842022-12-06 Real-World Experience with a 60-mm-Long Stent in the Setting of Primary Percutaneous Coronary Intervention Thevan, Babu Abdulrahman, Abdulkarim Subbramaniyam, Suddharsan Chachar, Tarique Shahzad Yousif, Nooraldaem Noor, Husam A. Amin, Haitham Abdulqader, Fuad Shivappa, Sadananda Heart Views Original Article INTRODUCTION: Primary percutaneous coronary intervention (PPCI) represents a timely procedure that requires speedy revascularization. Moreover, PPCI in diffuse coronary lesions remains to be challenging even in the hands of experienced operators as the use of a long stent may increase the difficulty of the procedure in terms of stent delivery, deployment, and optimization. However, the practicability and clinical outcomes of deployment of a 60-mm-long stent in the setting of PPCI remain to be determined. METHODS: The study is a retrospective observational analysis in a prospective cohort. The prospectively gathered data of consecutive patients from June 2016 to December 2019, who underwent PPCI with BioMime sirolimus-eluting stents 2.5–3.0/60 mm or 3.0–3.5/60 mm were analyzed at 1 year regarding the primary outcome of major adverse cardiovascular and cerebrovascular events (MACCE) and target lesion revascularization (TLR). RESULTS: A total of 88 cases were included in the study; 23 cases underwent PPCI, whereas 65 underwent nonPPCI. The PPCI group had a mean age of 65.7 ± 10.9 years compared with 63.3 ± 9.6 years (P = 0.34) in the nonPPCI group. Eighty-three percentage of PPCI were males compared with 94% of their nonPPCI counterparts (P = 0.20). In addition, the prevalence of hypertension was more common in the PPCI group (87% vs. 63%, P = 0.03). There was no statistically significant difference between the two groups regarding other comorbidities. The most common culprit vessel was the left anterior descending artery (57%) in the PPCI group and the right coronary artery (58%) in the nonPPCI. The use of a stent with a diameter of 2.5–3.0 mm was more common in both groups (61% in PPCI vs. 66% in nonPPCI, P = 0.8). MACCE occurred in four patients during a year of follow-up. One occurred in the PPCI group (4%) compared with three in the nonPPCI group (5%) (P = 1.00). TLR was required in two cases, one in each group (4% vs. 2%, P = 0.46). CONCLUSION: The use of a 60-mm-long stent in the setting of PPCI has an excellent 12-month outcome in procedural success, MACCE, and TLR. Large randomized studies are required to confirm these results. Wolters Kluwer - Medknow 2022 2022-10-22 /pmc/articles/PMC9721184/ /pubmed/36479168 http://dx.doi.org/10.4103/heartviews.heartviews_2_22 Text en Copyright: © 2022 Heart Views https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Thevan, Babu
Abdulrahman, Abdulkarim
Subbramaniyam, Suddharsan
Chachar, Tarique Shahzad
Yousif, Nooraldaem
Noor, Husam A.
Amin, Haitham
Abdulqader, Fuad
Shivappa, Sadananda
Real-World Experience with a 60-mm-Long Stent in the Setting of Primary Percutaneous Coronary Intervention
title Real-World Experience with a 60-mm-Long Stent in the Setting of Primary Percutaneous Coronary Intervention
title_full Real-World Experience with a 60-mm-Long Stent in the Setting of Primary Percutaneous Coronary Intervention
title_fullStr Real-World Experience with a 60-mm-Long Stent in the Setting of Primary Percutaneous Coronary Intervention
title_full_unstemmed Real-World Experience with a 60-mm-Long Stent in the Setting of Primary Percutaneous Coronary Intervention
title_short Real-World Experience with a 60-mm-Long Stent in the Setting of Primary Percutaneous Coronary Intervention
title_sort real-world experience with a 60-mm-long stent in the setting of primary percutaneous coronary intervention
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721184/
https://www.ncbi.nlm.nih.gov/pubmed/36479168
http://dx.doi.org/10.4103/heartviews.heartviews_2_22
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