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Inhibitory activities of alginate phosphate and sulfate derivatives against SARS-CoV-2 in vitro

Alginate derivatives have been demonstrated remarkable antiviral activities. Here we firstly identified polymannuronate phosphate (PMP) as a highly potential anti-SARS-CoV-2 agent. The structure-activity relationship showed polymannuronate monophosphate (PMPD, Mw: 5.8 kDa, P%: 8.7 %) was the most ef...

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Detalles Bibliográficos
Autores principales:	Yang, Cheng, Li, Dan, Wang, Shixin, Xu, Meijie, Wang, Dingfu, Li, Xin, Xu, Ximing, Li, Chunxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721379/ https://www.ncbi.nlm.nih.gov/pubmed/36481336 http://dx.doi.org/10.1016/j.ijbiomac.2022.11.311

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