Description of CRISPR-Cas9 development and its prospects in human papillomavirus-driven cancer treatment

Human papillomaviruses (HPVs) have been recognized as the etiologic agents of various cancers and are called HPV-driven cancers. Concerning HPV-mediated carcinogenic action, gene therapy can cure cancer at the molecular level by means of the correction of specific genes or sites. CRISPR-Cas9, as a n...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Yuhao, Zhao, Zhen, Ma, Xuelei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721393/
https://www.ncbi.nlm.nih.gov/pubmed/36479105
http://dx.doi.org/10.3389/fimmu.2022.1037124
_version_ 1784843764574978048
author Wei, Yuhao
Zhao, Zhen
Ma, Xuelei
author_facet Wei, Yuhao
Zhao, Zhen
Ma, Xuelei
author_sort Wei, Yuhao
collection PubMed
description Human papillomaviruses (HPVs) have been recognized as the etiologic agents of various cancers and are called HPV-driven cancers. Concerning HPV-mediated carcinogenic action, gene therapy can cure cancer at the molecular level by means of the correction of specific genes or sites. CRISPR-Cas9, as a novel genetic editing technique, can correct errors in the genome and change the gene expression and function in cells efficiently, quickly, and with relative ease. Herein, we overviewed studies of CRISPR-mediated gene remedies for HPV-driven cancers and summarized the potential applications of CRISPR-Cas9 in gene therapy for cancer.
format Online
Article
Text
id pubmed-9721393
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-97213932022-12-06 Description of CRISPR-Cas9 development and its prospects in human papillomavirus-driven cancer treatment Wei, Yuhao Zhao, Zhen Ma, Xuelei Front Immunol Immunology Human papillomaviruses (HPVs) have been recognized as the etiologic agents of various cancers and are called HPV-driven cancers. Concerning HPV-mediated carcinogenic action, gene therapy can cure cancer at the molecular level by means of the correction of specific genes or sites. CRISPR-Cas9, as a novel genetic editing technique, can correct errors in the genome and change the gene expression and function in cells efficiently, quickly, and with relative ease. Herein, we overviewed studies of CRISPR-mediated gene remedies for HPV-driven cancers and summarized the potential applications of CRISPR-Cas9 in gene therapy for cancer. Frontiers Media S.A. 2022-11-21 /pmc/articles/PMC9721393/ /pubmed/36479105 http://dx.doi.org/10.3389/fimmu.2022.1037124 Text en Copyright © 2022 Wei, Zhao and Ma https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Wei, Yuhao
Zhao, Zhen
Ma, Xuelei
Description of CRISPR-Cas9 development and its prospects in human papillomavirus-driven cancer treatment
title Description of CRISPR-Cas9 development and its prospects in human papillomavirus-driven cancer treatment
title_full Description of CRISPR-Cas9 development and its prospects in human papillomavirus-driven cancer treatment
title_fullStr Description of CRISPR-Cas9 development and its prospects in human papillomavirus-driven cancer treatment
title_full_unstemmed Description of CRISPR-Cas9 development and its prospects in human papillomavirus-driven cancer treatment
title_short Description of CRISPR-Cas9 development and its prospects in human papillomavirus-driven cancer treatment
title_sort description of crispr-cas9 development and its prospects in human papillomavirus-driven cancer treatment
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721393/
https://www.ncbi.nlm.nih.gov/pubmed/36479105
http://dx.doi.org/10.3389/fimmu.2022.1037124
work_keys_str_mv AT weiyuhao descriptionofcrisprcas9developmentanditsprospectsinhumanpapillomavirusdrivencancertreatment
AT zhaozhen descriptionofcrisprcas9developmentanditsprospectsinhumanpapillomavirusdrivencancertreatment
AT maxuelei descriptionofcrisprcas9developmentanditsprospectsinhumanpapillomavirusdrivencancertreatment

Ejemplares similares