Fibroblasts and macrophages cooperate to create a pro-tumorigenic and immune resistant environment via activation of TGF-β/IL-6 pathway in neuroblastoma

Tumor-associated macrophages (TAM) and cancer-associated fibroblasts (CAF) and their precursor mesenchymal stromal cells (MSC) are often detected together in tumors, but how they cooperate is not well understood. Here, we show that TAM and CAF are the most abundant nonmalignant cells and are present...

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Detalles Bibliográficos
Autores principales: Louault, Kevin, Porras, Tania, Lee, Meng-Hua, Muthugounder, Sakunthala, Kennedy, Rebekah J., Blavier, Laurence, Sarte, Emily, Fernandez, G. Esteban, Yang, Fusheng, Pawel, Bruce R., Shimada, Hiroyuki, Asgharzadeh, Shahab, DeClerck, Yves A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721439/
https://www.ncbi.nlm.nih.gov/pubmed/36479153
http://dx.doi.org/10.1080/2162402X.2022.2146860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721439/
https://www.ncbi.nlm.nih.gov/pubmed/36479153
http://dx.doi.org/10.1080/2162402X.2022.2146860

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