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Fibroblasts and macrophages cooperate to create a pro-tumorigenic and immune resistant environment via activation of TGF-β/IL-6 pathway in neuroblastoma
Tumor-associated macrophages (TAM) and cancer-associated fibroblasts (CAF) and their precursor mesenchymal stromal cells (MSC) are often detected together in tumors, but how they cooperate is not well understood. Here, we show that TAM and CAF are the most abundant nonmalignant cells and are present...
Autores principales: | Louault, Kevin, Porras, Tania, Lee, Meng-Hua, Muthugounder, Sakunthala, Kennedy, Rebekah J., Blavier, Laurence, Sarte, Emily, Fernandez, G. Esteban, Yang, Fusheng, Pawel, Bruce R., Shimada, Hiroyuki, Asgharzadeh, Shahab, DeClerck, Yves A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721439/ https://www.ncbi.nlm.nih.gov/pubmed/36479153 http://dx.doi.org/10.1080/2162402X.2022.2146860 |
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