Human Trypanosoma cruzi chronic infection leads to individual level steady-state parasitemia: Implications for drug-trial optimization in Chagas disease

Currently available drugs against Trypanosoma cruzi infection, which causes 12000 deaths annually, have limitations in their efficacy, safety and tolerability. The evaluation of therapeutic responses to available and new compounds is based on parasite detection in the bloodstream but remains challen...

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Detalles Bibliográficos
Autores principales: De Salazar, Pablo M., Sosa-Estani, Sergio, Salvador, Fernando, Sulleiro, Elena, Sánchez-Montalvá, Adrián, Ribeiro, Isabela, Molina, Israel, Buckee, Caroline O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721471/
https://www.ncbi.nlm.nih.gov/pubmed/36409773
http://dx.doi.org/10.1371/journal.pntd.0010828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721471/
https://www.ncbi.nlm.nih.gov/pubmed/36409773
http://dx.doi.org/10.1371/journal.pntd.0010828

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