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Human Trypanosoma cruzi chronic infection leads to individual level steady-state parasitemia: Implications for drug-trial optimization in Chagas disease
Currently available drugs against Trypanosoma cruzi infection, which causes 12000 deaths annually, have limitations in their efficacy, safety and tolerability. The evaluation of therapeutic responses to available and new compounds is based on parasite detection in the bloodstream but remains challen...
Autores principales: | De Salazar, Pablo M., Sosa-Estani, Sergio, Salvador, Fernando, Sulleiro, Elena, Sánchez-Montalvá, Adrián, Ribeiro, Isabela, Molina, Israel, Buckee, Caroline O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721471/ https://www.ncbi.nlm.nih.gov/pubmed/36409773 http://dx.doi.org/10.1371/journal.pntd.0010828 |
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