Solubility Enhancement of a Poorly Water-Soluble Drug Using Hydrotropy and Mixed Hydrotropy-Based Solid Dispersion Techniques

PURPOSE: The biopharmaceutics classification system places rosuvastatin calcium in class II has a low and fluctuating oral bioavailability. The research focus is to maximize rosuvastatin calcium solubility in water and dissolution rate by employing and combining various hydrotropic agents to make a...

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Detalles Bibliográficos
Autores principales: Abdullah Ali, Hezha, Kamal Omer, Hunar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722314/
https://www.ncbi.nlm.nih.gov/pubmed/36479276
http://dx.doi.org/10.1155/2022/7161660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722314/
https://www.ncbi.nlm.nih.gov/pubmed/36479276
http://dx.doi.org/10.1155/2022/7161660

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