MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) in adolescents at West Bengal, India

Mucin 4 (MUC4) and matrix metalloproteinase 7 (MMP7) have been reported to be associated with chronic periodontitis as seen in gingival tissue biopsies. Therefore, it is of interest to estimate the levels of MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) samples of periodontitis in adol...

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Autores principales: Chattopadhyay, Sayan, Arora, Rachita, Kishor, Amit, Singh, Shivani, Alok, Abhijeet, Mitra, Mainak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722411/
https://www.ncbi.nlm.nih.gov/pubmed/36518149
http://dx.doi.org/10.6026/97320630018165
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author Chattopadhyay, Sayan
Arora, Rachita
Kishor, Amit
Singh, Shivani
Alok, Abhijeet
Mitra, Mainak
author_facet Chattopadhyay, Sayan
Arora, Rachita
Kishor, Amit
Singh, Shivani
Alok, Abhijeet
Mitra, Mainak
author_sort Chattopadhyay, Sayan
collection PubMed
description Mucin 4 (MUC4) and matrix metalloproteinase 7 (MMP7) have been reported to be associated with chronic periodontitis as seen in gingival tissue biopsies. Therefore, it is of interest to estimate the levels of MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) samples of periodontitis in adolescents patients at West Bengal, India. MUC4 levels were significantly lower in saliva and GCF from periodontitis patients compared to healthy controls. However, MMP7 levels were found to be significantly higher in saliva and GCF from periodontitis patients. Thus, MUC4 and MMP7 are biomarkers for periodontitis diagnosis and towards further consideration.
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spelling pubmed-97224112022-12-13 MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) in adolescents at West Bengal, India Chattopadhyay, Sayan Arora, Rachita Kishor, Amit Singh, Shivani Alok, Abhijeet Mitra, Mainak Bioinformation Research Article Mucin 4 (MUC4) and matrix metalloproteinase 7 (MMP7) have been reported to be associated with chronic periodontitis as seen in gingival tissue biopsies. Therefore, it is of interest to estimate the levels of MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) samples of periodontitis in adolescents patients at West Bengal, India. MUC4 levels were significantly lower in saliva and GCF from periodontitis patients compared to healthy controls. However, MMP7 levels were found to be significantly higher in saliva and GCF from periodontitis patients. Thus, MUC4 and MMP7 are biomarkers for periodontitis diagnosis and towards further consideration. Biomedical Informatics 2022-03-31 /pmc/articles/PMC9722411/ /pubmed/36518149 http://dx.doi.org/10.6026/97320630018165 Text en © 2022 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Chattopadhyay, Sayan
Arora, Rachita
Kishor, Amit
Singh, Shivani
Alok, Abhijeet
Mitra, Mainak
MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) in adolescents at West Bengal, India
title MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) in adolescents at West Bengal, India
title_full MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) in adolescents at West Bengal, India
title_fullStr MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) in adolescents at West Bengal, India
title_full_unstemmed MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) in adolescents at West Bengal, India
title_short MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) in adolescents at West Bengal, India
title_sort muc4 and mmp7 in saliva and gingival crevicular fluid (gcf) in adolescents at west bengal, india
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722411/
https://www.ncbi.nlm.nih.gov/pubmed/36518149
http://dx.doi.org/10.6026/97320630018165
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