Cargando…
The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses
Hearing depends on fast and sustained calcium-dependent synaptic vesicle fusion at the ribbon synapses of cochlear inner hair cells (IHCs). The implication of the canonical neuronal SNARE complex in this exocytotic process has so far remained controversial. We investigated the role of SNAP-25, a key...
Autores principales: | Calvet, Charlotte, Peineau, Thibault, Benamer, Najate, Cornille, Maxence, Lelli, Andrea, Plion, Baptiste, Lahlou, Ghizlène, Fanchette, Julia, Nouaille, Sylvie, Boutet de Monvel, Jacques, Estivalet, Amrit, Jean, Philippe, Michel, Vincent, Sachse, Martin, Michalski, Nicolas, Avan, Paul, Petit, Christine, Dulon, Didier, Safieddine, Saaid |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722480/ https://www.ncbi.nlm.nih.gov/pubmed/36483015 http://dx.doi.org/10.1016/j.isci.2022.105628 |
Ejemplares similares
-
Otoferlin acts as a Ca(2+) sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses
por: Michalski, Nicolas, et al.
Publicado: (2017) -
Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model
por: Akil, Omar, et al.
Publicado: (2019) -
Towards the Clinical Application of Gene Therapy for Genetic Inner Ear Diseases
por: Lahlou, Ghizlene, et al.
Publicado: (2023) -
Synaptic Release Potentiation at Aging Auditory Ribbon Synapses
por: Peineau, Thibault, et al.
Publicado: (2021) -
Sequential exocytosis of insulin granules is associated with redistribution of SNAP25
por: Takahashi, Noriko, et al.
Publicado: (2004)