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FTO promotes innate immunity by controlling NOD1 expression via m(6)A-YTHDF2 manner in teleost

N6-methyladenosine (m(6)A), the most abundant internal mRNA modification in eukaryotes, plays a vital role in regulating innate immunity. However, its underlying mechanism remains largely unknown, especially in lower vertebrates. The results of the present study show that fat-mass- and obesity-assoc...

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Detalles Bibliográficos
Autores principales: Geng, Shang, Zheng, Weiwei, Zhao, Yan, Xu, Tianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722488/
https://www.ncbi.nlm.nih.gov/pubmed/36483010
http://dx.doi.org/10.1016/j.isci.2022.105646

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