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Planar aggregation of the influenza viral fusion peptide alters membrane structure and hydration, promoting poration
To infect, enveloped viruses employ spike protein, spearheaded by its amphipathic fusion peptide (FP), that upon activation extends out from the viral surface to embed into the target cellular membrane. Here we report that synthesized influenza virus FPs are membrane active, generating pores in gian...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722698/ https://www.ncbi.nlm.nih.gov/pubmed/36470871 http://dx.doi.org/10.1038/s41467-022-34576-z |