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Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G

An essential step in restricting HIV infectivity by the antiviral factor APOBEC3G is its incorporation into progeny virions via binding to HIV RNA. However, the mechanism of APOBEC3G capturing viral RNA is unknown. Here, we report crystal structures of a primate APOBEC3G bound to different types of...

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Detalles Bibliográficos
Autores principales:	Yang, Hanjing, Kim, Kyumin, Li, Shuxing, Pacheco, Josue, Chen, Xiaojiang S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722718/ https://www.ncbi.nlm.nih.gov/pubmed/36470880 http://dx.doi.org/10.1038/s41467-022-35201-9

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