Delineating the dynamic evolution from preneoplasia to invasive lung adenocarcinoma by integrating single-cell RNA sequencing and spatial transcriptomics

The cell ecology and spatial niche implicated in the dynamic and sequential process of lung adenocarcinoma (LUAD) from adenocarcinoma in situ (AIS) to minimally invasive adenocarcinoma (MIA) and subsequent invasive adenocarcinoma (IAC) have not yet been elucidated. Here, we performed an integrative...

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Detalles Bibliográficos
Autores principales: Zhu, Jianfei, Fan, Yue, Xiong, Yanlu, Wang, Wenchen, Chen, Jiakuan, Xia, Yanmin, Lei, Jie, Gong, Li, Sun, Shiquan, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722784/
https://www.ncbi.nlm.nih.gov/pubmed/36434043
http://dx.doi.org/10.1038/s12276-022-00896-9

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