Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model

Down syndrome (DS) is the most common chromosomal abnormality in live-born infants and is caused by trisomy of chromosome 21. Most individuals with DS display craniofacial dysmorphology, including reduced sizes of the skull, maxilla, and mandible. However, the underlying pathogenesis remains largely...

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Detalles Bibliográficos
Autores principales: Liu, Huanyao, Huang, Shanshan, Wang, Weijia, Wang, Huiyan, Huang, Weijun, Zhai, Zhichen, Wang, Ding, Fan, Yubao, Sun, Jiaqi, Li, Dairui, Chiu, Weicheng, Lai, Xingqiang, Zeng, Jixiao, Ke, Qiong, Wang, Tao, Xiang, Andy Peng, Yuan, Yong, Zhang, Xinchun, Li, Weiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722909/
https://www.ncbi.nlm.nih.gov/pubmed/36470861
http://dx.doi.org/10.1038/s41419-022-05481-6

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